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Anti-SRD5A2 monoclonal antibody
Pre-made anti-SRD5A2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SRD5A2/SRD5A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0020-Ab-1/ GM-Tg-hg-IP0020-Ab-2 | Anti-Human SRD5A2 monoclonal antibody | Human |
| GM-Tg-rg-IP0020-Ab-1/ GM-Tg-rg-IP0020-Ab-2 | Anti-Rat SRD5A2 monoclonal antibody | Rat |
| GM-Tg-mg-IP0020-Ab-1/ GM-Tg-mg-IP0020-Ab-2 | Anti-Mouse SRD5A2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0020-Ab-1/ GM-Tg-cynog-IP0020-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SRD5A2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0020-Ab-1/ GM-Tg-felg-IP0020-Ab-2 | Anti-Feline SRD5A2 monoclonal antibody | Feline |
| GM-Tg-cang-IP0020-Ab-1/ GM-Tg-cang-IP0020-Ab-2 | Anti-Canine SRD5A2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0020-Ab-1/ GM-Tg-bovg-IP0020-Ab-2 | Anti-Bovine SRD5A2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0020-Ab-1/ GM-Tg-equg-IP0020-Ab-2 | Anti-Equine SRD5A2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0020-Ab-1/ GM-Tg-hg-IP0020-Ab-2; GM-Tg-rg-IP0020-Ab-1/ GM-Tg-rg-IP0020-Ab-2; GM-Tg-mg-IP0020-Ab-1/ GM-Tg-mg-IP0020-Ab-2; GM-Tg-cynog-IP0020-Ab-1/ GM-Tg-cynog-IP0020-Ab-2; GM-Tg-felg-IP0020-Ab-1/ GM-Tg-felg-IP0020-Ab-2; GM-Tg-cang-IP0020-Ab-1/ GM-Tg-cang-IP0020-Ab-2; GM-Tg-bovg-IP0020-Ab-1/ GM-Tg-bovg-IP0020-Ab-2; GM-Tg-equg-IP0020-Ab-1/ GM-Tg-equg-IP0020-Ab-2 |
| Products Name | Anti-SRD5A2 monoclonal antibody |
| Format | mab |
| Target Name | SRD5A2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SRD5A2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0020-Ag-1 | Recombinant multi-species S5A2/ SRD5A2 protein |
| ORF Viral Vector | pGMLP004602 | human SRD5A2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004602 | human SRD5A2 Lentivirus particle |
| ORF Viral Vector | pGMLPm004612 | mouse Srd5a2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004612 | mouse Srd5a2 Lentivirus particle |
Target information
| Target ID | GM-IP0020 |
| Target Name | SRD5A2 |
| Gene ID | 6716,94224,64677,705676,403715,101086898,527024,100070655 |
| Gene Symbol and Synonyms | 5ART2,S5AR 2,SRD5A2 |
| Uniprot Accession | P31213,P31214 |
| Uniprot Entry Name | S5A2_HUMAN,S5A2_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Prostate disease |
| Gene Ensembl | ENSG00000277893 |
| Target Classification | N/A |
The target: SRD5A2, gene name: SRD5A2, also named as . This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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