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Anti-PEMT monoclonal antibody
Pre-made anti-PEMT monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PEMT/PEMT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0167-Ab-1/ GM-Tg-hg-IP0167-Ab-2 | Anti-Human PEMT monoclonal antibody | Human |
| GM-Tg-rg-IP0167-Ab-1/ GM-Tg-rg-IP0167-Ab-2 | Anti-Rat PEMT monoclonal antibody | Rat |
| GM-Tg-mg-IP0167-Ab-1/ GM-Tg-mg-IP0167-Ab-2 | Anti-Mouse PEMT monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0167-Ab-1/ GM-Tg-cynog-IP0167-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PEMT monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0167-Ab-1/ GM-Tg-felg-IP0167-Ab-2 | Anti-Feline PEMT monoclonal antibody | Feline |
| GM-Tg-cang-IP0167-Ab-1/ GM-Tg-cang-IP0167-Ab-2 | Anti-Canine PEMT monoclonal antibody | Canine |
| GM-Tg-bovg-IP0167-Ab-1/ GM-Tg-bovg-IP0167-Ab-2 | Anti-Bovine PEMT monoclonal antibody | Bovine |
| GM-Tg-equg-IP0167-Ab-1/ GM-Tg-equg-IP0167-Ab-2 | Anti-Equine PEMT monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0167-Ab-1/ GM-Tg-hg-IP0167-Ab-2; GM-Tg-rg-IP0167-Ab-1/ GM-Tg-rg-IP0167-Ab-2; GM-Tg-mg-IP0167-Ab-1/ GM-Tg-mg-IP0167-Ab-2; GM-Tg-cynog-IP0167-Ab-1/ GM-Tg-cynog-IP0167-Ab-2; GM-Tg-felg-IP0167-Ab-1/ GM-Tg-felg-IP0167-Ab-2; GM-Tg-cang-IP0167-Ab-1/ GM-Tg-cang-IP0167-Ab-2; GM-Tg-bovg-IP0167-Ab-1/ GM-Tg-bovg-IP0167-Ab-2; GM-Tg-equg-IP0167-Ab-1/ GM-Tg-equg-IP0167-Ab-2 |
| Products Name | Anti-PEMT monoclonal antibody |
| Format | mab |
| Target Name | PEMT |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PEMT monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0167-Ag-1 | Recombinant multi-species PEMT/ PEAMT/ PEMPT2 protein |
| ORF Viral Vector | pGMLP004853 | human PEMT Lentivirus plasmid |
| ORF Viral Vector | vGMLP004853 | human PEMT Lentivirus particle |
| ORF Viral Vector | pGMAD000254 | rat Pemt Adenovirus plasmid |
| ORF Viral Vector | vGMAD000254 | rat Pemt Adenovirus particle |
Target information
| Target ID | GM-IP0167 |
| Target Name | PEMT |
| Gene ID | 10400,18618,25511,699083,479526,101088035,360197,100050945 |
| Gene Symbol and Synonyms | PEAMT,PEMPT,Pempt2,PEMT,PEMT2,PHOMETH,PLMT,PNMT |
| Uniprot Accession | Q9UBM1,Q08388,Q7YRH6 |
| Uniprot Entry Name | PEMT_HUMAN,PEMT_RAT,PEMT_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000133027 |
| Target Classification | N/A |
The target: PEMT, gene name: PEMT, also named as PEAMT, PEMPT2, PLMT, PNMT, PEMT. Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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