Anti-RNS12/ RNASE12/ HEL-S-85p functional antibody

Anti-RNS12/ RNASE12/ HEL-S-85p functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to RNASE12/RNASE12 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1245-Ab-1/ GM-Tg-hg-SE1245-Ab-2Anti-Human RNASE12 monoclonal antibodyHuman
GM-Tg-rg-SE1245-Ab-1/ GM-Tg-rg-SE1245-Ab-2Anti-Rat RNASE12 monoclonal antibodyRat
GM-Tg-mg-SE1245-Ab-1/ GM-Tg-mg-SE1245-Ab-2Anti-Mouse RNASE12 monoclonal antibodyMouse
GM-Tg-cynog-SE1245-Ab-1/ GM-Tg-cynog-SE1245-Ab-2Anti-Cynomolgus/ Rhesus macaque RNASE12 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1245-Ab-1/ GM-Tg-felg-SE1245-Ab-2Anti-Feline RNASE12 monoclonal antibodyFeline
GM-Tg-cang-SE1245-Ab-1/ GM-Tg-cang-SE1245-Ab-2Anti-Canine RNASE12 monoclonal antibodyCanine
GM-Tg-bovg-SE1245-Ab-1/ GM-Tg-bovg-SE1245-Ab-2Anti-Bovine RNASE12 monoclonal antibodyBovine
GM-Tg-equg-SE1245-Ab-1/ GM-Tg-equg-SE1245-Ab-2Anti-Equine RNASE12 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-SE1245-Ab-1/ GM-Tg-hg-SE1245-Ab-2; GM-Tg-rg-SE1245-Ab-1/ GM-Tg-rg-SE1245-Ab-2;
GM-Tg-mg-SE1245-Ab-1/ GM-Tg-mg-SE1245-Ab-2; GM-Tg-cynog-SE1245-Ab-1/ GM-Tg-cynog-SE1245-Ab-2;
GM-Tg-felg-SE1245-Ab-1/ GM-Tg-felg-SE1245-Ab-2; GM-Tg-cang-SE1245-Ab-1/ GM-Tg-cang-SE1245-Ab-2;
GM-Tg-bovg-SE1245-Ab-1/ GM-Tg-bovg-SE1245-Ab-2; GM-Tg-equg-SE1245-Ab-1/ GM-Tg-equg-SE1245-Ab-2
Products NameAnti-RNASE12 monoclonal antibody
Target NameRNASE12
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-RNASE12 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1245-Ag-1Recombinant multi-species RNS12/ RNASE12/ HEL-S-85p protein

    Target information

    Target IDGM-SE1245
    Target NameRNASE12
    Gene ID493901,497106,364302,100688089,101081986,100297737,100058840
    Gene Symbol and SynonymsHEL-S-85p,RAI1,RGD1307829,RNASE12
    Uniprot AccessionQ5GAN4,Q5GAL8
    Uniprot Entry NameRNS12_HUMAN,RNS12_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Gene EnsemblENSG00000258436
    Target ClassificationN/A

    The target: RNASE12, gene name: RNASE12, also named as HEL-S-85p, RAI1. Predicted to enable nucleic acid binding activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.