Anti-SEM3G/ SEMA3G/ sem2 functional antibody

Anti-SEM3G/ SEMA3G/ sem2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SEMA3G/SEMA3G products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1274-Ab-1/ GM-Tg-hg-SE1274-Ab-2Anti-Human SEMA3G monoclonal antibodyHuman
GM-Tg-rg-SE1274-Ab-1/ GM-Tg-rg-SE1274-Ab-2Anti-Rat SEMA3G monoclonal antibodyRat
GM-Tg-mg-SE1274-Ab-1/ GM-Tg-mg-SE1274-Ab-2Anti-Mouse SEMA3G monoclonal antibodyMouse
GM-Tg-cynog-SE1274-Ab-1/ GM-Tg-cynog-SE1274-Ab-2Anti-Cynomolgus/ Rhesus macaque SEMA3G monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1274-Ab-1/ GM-Tg-felg-SE1274-Ab-2Anti-Feline SEMA3G monoclonal antibodyFeline
GM-Tg-cang-SE1274-Ab-1/ GM-Tg-cang-SE1274-Ab-2Anti-Canine SEMA3G monoclonal antibodyCanine
GM-Tg-bovg-SE1274-Ab-1/ GM-Tg-bovg-SE1274-Ab-2Anti-Bovine SEMA3G monoclonal antibodyBovine
GM-Tg-equg-SE1274-Ab-1/ GM-Tg-equg-SE1274-Ab-2Anti-Equine SEMA3G monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1274-Ab-1/ GM-Tg-hg-SE1274-Ab-2; GM-Tg-rg-SE1274-Ab-1/ GM-Tg-rg-SE1274-Ab-2;
GM-Tg-mg-SE1274-Ab-1/ GM-Tg-mg-SE1274-Ab-2; GM-Tg-cynog-SE1274-Ab-1/ GM-Tg-cynog-SE1274-Ab-2;
GM-Tg-felg-SE1274-Ab-1/ GM-Tg-felg-SE1274-Ab-2; GM-Tg-cang-SE1274-Ab-1/ GM-Tg-cang-SE1274-Ab-2;
GM-Tg-bovg-SE1274-Ab-1/ GM-Tg-bovg-SE1274-Ab-2; GM-Tg-equg-SE1274-Ab-1/ GM-Tg-equg-SE1274-Ab-2
Products NameAnti-SEMA3G monoclonal antibody
Formatmab
Target NameSEMA3G
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SEMA3G benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1274-Ag-1Recombinant multi-species SEM3G/ SEMA3G/ sem2 protein


    Target information

    Target IDGM-SE1274
    Target NameSEMA3G
    Gene ID56920,218877,290562,697162,484736,101082730,100299041,100060213
    Gene Symbol and SynonymsCSG53,RGD1306079,sem2,SEMA3G
    Uniprot AccessionQ9NS98
    Uniprot Entry NameSEM3G_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000010319
    Target ClassificationN/A

    The target: SEMA3G, gene name: SEMA3G, also named as sem2. The transcription of this gene is activated by PPAR-gamma, and the resulting protein product plays a role in endothelial cell migration. Expression of this gene also inhibits tumor cell migration and invasion. [provided by RefSeq, Jul 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.