Anti-SFRP2/ FRP-2/ SARP1 functional antibody

Anti-SFRP2/ FRP-2/ SARP1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SFRP2/SFRP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1284-Ab-1/ GM-Tg-hg-SE1284-Ab-2Anti-Human SFRP2 monoclonal antibodyHuman
GM-Tg-rg-SE1284-Ab-1/ GM-Tg-rg-SE1284-Ab-2Anti-Rat SFRP2 monoclonal antibodyRat
GM-Tg-mg-SE1284-Ab-1/ GM-Tg-mg-SE1284-Ab-2Anti-Mouse SFRP2 monoclonal antibodyMouse
GM-Tg-cynog-SE1284-Ab-1/ GM-Tg-cynog-SE1284-Ab-2Anti-Cynomolgus/ Rhesus macaque SFRP2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1284-Ab-1/ GM-Tg-felg-SE1284-Ab-2Anti-Feline SFRP2 monoclonal antibodyFeline
GM-Tg-cang-SE1284-Ab-1/ GM-Tg-cang-SE1284-Ab-2Anti-Canine SFRP2 monoclonal antibodyCanine
GM-Tg-bovg-SE1284-Ab-1/ GM-Tg-bovg-SE1284-Ab-2Anti-Bovine SFRP2 monoclonal antibodyBovine
GM-Tg-equg-SE1284-Ab-1/ GM-Tg-equg-SE1284-Ab-2Anti-Equine SFRP2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-SE1284-Ab-1/ GM-Tg-hg-SE1284-Ab-2; GM-Tg-rg-SE1284-Ab-1/ GM-Tg-rg-SE1284-Ab-2;
GM-Tg-mg-SE1284-Ab-1/ GM-Tg-mg-SE1284-Ab-2; GM-Tg-cynog-SE1284-Ab-1/ GM-Tg-cynog-SE1284-Ab-2;
GM-Tg-felg-SE1284-Ab-1/ GM-Tg-felg-SE1284-Ab-2; GM-Tg-cang-SE1284-Ab-1/ GM-Tg-cang-SE1284-Ab-2;
GM-Tg-bovg-SE1284-Ab-1/ GM-Tg-bovg-SE1284-Ab-2; GM-Tg-equg-SE1284-Ab-1/ GM-Tg-equg-SE1284-Ab-2
Products NameAnti-SFRP2 monoclonal antibody
Target NameSFRP2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-SFRP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1284-Ag-1Recombinant multi-species SFRP2/ FRP-2/ SARP1 protein
    ORF Viral VectorvGMLP003519human SFRP2 Lentivirus particle
    ORF Viral VectorpGMLP004043human SFRP2 Lentivirus plasmid
    ORF Viral VectorpGMLP003519human SFRP2 Lentivirus plasmid
    ORF Viral VectorvGMLP004043human SFRP2 Lentivirus particle
    ORF Viral VectorpGMLPm000444mouse Sfrp2 Lentivirus plasmid
    ORF Viral VectorvGMLPm000444mouse Sfrp2 Lentivirus particle

    Target information

    Target IDGM-SE1284
    Target NameSFRP2
    Gene ID6423,20319,310552,699915,475471,101093851,510821,100069959
    Gene Symbol and SynonymsFRP-2,SARP1,SDF-5,Sdf5,SFRP-2,SFRP2
    Uniprot AccessionQ96HF1,Q863H1
    Uniprot Entry NameSFRP2_HUMAN,SFRP2_CANLF
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Gene EnsemblENSG00000145423
    Target ClassificationTumor-associated antigen (TAA)

    The target: SFRP2, gene name: SFRP2, also named as FRP-2, SARP1, SDF-5. This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.