Anti-SPON2/ DIL-1/ DIL1 functional antibody

Anti-SPON2/ DIL-1/ DIL1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SPON2/SPON2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1318-Ab-1/ GM-Tg-hg-SE1318-Ab-2Anti-Human SPON2 monoclonal antibodyHuman
GM-Tg-rg-SE1318-Ab-1/ GM-Tg-rg-SE1318-Ab-2Anti-Rat SPON2 monoclonal antibodyRat
GM-Tg-mg-SE1318-Ab-1/ GM-Tg-mg-SE1318-Ab-2Anti-Mouse SPON2 monoclonal antibodyMouse
GM-Tg-cynog-SE1318-Ab-1/ GM-Tg-cynog-SE1318-Ab-2Anti-Cynomolgus/ Rhesus macaque SPON2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1318-Ab-1/ GM-Tg-felg-SE1318-Ab-2Anti-Feline SPON2 monoclonal antibodyFeline
GM-Tg-cang-SE1318-Ab-1/ GM-Tg-cang-SE1318-Ab-2Anti-Canine SPON2 monoclonal antibodyCanine
GM-Tg-bovg-SE1318-Ab-1/ GM-Tg-bovg-SE1318-Ab-2Anti-Bovine SPON2 monoclonal antibodyBovine
GM-Tg-equg-SE1318-Ab-1/ GM-Tg-equg-SE1318-Ab-2Anti-Equine SPON2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-SE1318-Ab-1/ GM-Tg-hg-SE1318-Ab-2; GM-Tg-rg-SE1318-Ab-1/ GM-Tg-rg-SE1318-Ab-2;
GM-Tg-mg-SE1318-Ab-1/ GM-Tg-mg-SE1318-Ab-2; GM-Tg-cynog-SE1318-Ab-1/ GM-Tg-cynog-SE1318-Ab-2;
GM-Tg-felg-SE1318-Ab-1/ GM-Tg-felg-SE1318-Ab-2; GM-Tg-cang-SE1318-Ab-1/ GM-Tg-cang-SE1318-Ab-2;
GM-Tg-bovg-SE1318-Ab-1/ GM-Tg-bovg-SE1318-Ab-2; GM-Tg-equg-SE1318-Ab-1/ GM-Tg-equg-SE1318-Ab-2
Products NameAnti-SPON2 monoclonal antibody
Target NameSPON2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-SPON2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

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    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1318-Ag-1Recombinant multi-species SPON2/ DIL-1/ DIL1 protein

    Target information

    Target IDGM-SE1318
    Target NameSPON2
    Gene ID10417,171569,702450,102155429,101081629,513844,100052156
    Gene Symbol and SynonymsDIL-1,DIL1,M-SPONDIN,MINDIN,SPON2
    Uniprot AccessionQ9BUD6,Q9WV75
    Uniprot Entry NameSPON2_HUMAN,SPON2_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Gene EnsemblENSG00000159674
    Target ClassificationN/A

    The target: SPON2, gene name: SPON2, also named as DIL-1, DIL1, M-SPONDIN, MINDIN. Predicted to enable antigen binding activity; lipopolysaccharide binding activity; and metal ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within several processes, including defense response to other organism; opsonization; and positive regulation of cytokine production. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.