Anti-VWCE/ URG11/ VWC1 functional antibody

Anti-VWCE/ URG11/ VWC1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to VWCE/VWCE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1369-Ab-1/ GM-Tg-hg-SE1369-Ab-2Anti-Human VWCE monoclonal antibodyHuman
GM-Tg-rg-SE1369-Ab-1/ GM-Tg-rg-SE1369-Ab-2Anti-Rat VWCE monoclonal antibodyRat
GM-Tg-mg-SE1369-Ab-1/ GM-Tg-mg-SE1369-Ab-2Anti-Mouse VWCE monoclonal antibodyMouse
GM-Tg-cynog-SE1369-Ab-1/ GM-Tg-cynog-SE1369-Ab-2Anti-Cynomolgus/ Rhesus macaque VWCE monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1369-Ab-1/ GM-Tg-felg-SE1369-Ab-2Anti-Feline VWCE monoclonal antibodyFeline
GM-Tg-cang-SE1369-Ab-1/ GM-Tg-cang-SE1369-Ab-2Anti-Canine VWCE monoclonal antibodyCanine
GM-Tg-bovg-SE1369-Ab-1/ GM-Tg-bovg-SE1369-Ab-2Anti-Bovine VWCE monoclonal antibodyBovine
GM-Tg-equg-SE1369-Ab-1/ GM-Tg-equg-SE1369-Ab-2Anti-Equine VWCE monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1369-Ab-1/ GM-Tg-hg-SE1369-Ab-2; GM-Tg-rg-SE1369-Ab-1/ GM-Tg-rg-SE1369-Ab-2;
GM-Tg-mg-SE1369-Ab-1/ GM-Tg-mg-SE1369-Ab-2; GM-Tg-cynog-SE1369-Ab-1/ GM-Tg-cynog-SE1369-Ab-2;
GM-Tg-felg-SE1369-Ab-1/ GM-Tg-felg-SE1369-Ab-2; GM-Tg-cang-SE1369-Ab-1/ GM-Tg-cang-SE1369-Ab-2;
GM-Tg-bovg-SE1369-Ab-1/ GM-Tg-bovg-SE1369-Ab-2; GM-Tg-equg-SE1369-Ab-1/ GM-Tg-equg-SE1369-Ab-2
Products NameAnti-VWCE monoclonal antibody
Formatmab
Target NameVWCE
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-VWCE benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1369-Ag-1Recombinant multi-species VWCE/ URG11/ VWC1 protein


    Target information

    Target IDGM-SE1369
    Target NameVWCE
    Gene ID220001,71768,309209,694385,483801,101083799,787487,100059568
    Gene Symbol and Synonyms1300015B04Rik,RGD1309910,URG11,VWC1,VWCE
    Uniprot AccessionQ96DN2
    Uniprot Entry NameVWCE_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000167992
    Target ClassificationN/A

    The target: VWCE, gene name: VWCE, also named as URG11, VWC1. Predicted to enable calcium ion binding activity. Involved in cellular response to virus. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.