Anti-WFDC6/ C20orf171/ HEL-S-295 functional antibody

Anti-WFDC6/ C20orf171/ HEL-S-295 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to WFDC6/WFDC6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1378-Ab-1/ GM-Tg-hg-SE1378-Ab-2Anti-Human WFDC6 monoclonal antibodyHuman
GM-Tg-rg-SE1378-Ab-1/ GM-Tg-rg-SE1378-Ab-2Anti-Rat WFDC6 monoclonal antibodyRat
GM-Tg-mg-SE1378-Ab-1/ GM-Tg-mg-SE1378-Ab-2Anti-Mouse WFDC6 monoclonal antibodyMouse
GM-Tg-cynog-SE1378-Ab-1/ GM-Tg-cynog-SE1378-Ab-2Anti-Cynomolgus/ Rhesus macaque WFDC6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1378-Ab-1/ GM-Tg-felg-SE1378-Ab-2Anti-Feline WFDC6 monoclonal antibodyFeline
GM-Tg-cang-SE1378-Ab-1/ GM-Tg-cang-SE1378-Ab-2Anti-Canine WFDC6 monoclonal antibodyCanine
GM-Tg-bovg-SE1378-Ab-1/ GM-Tg-bovg-SE1378-Ab-2Anti-Bovine WFDC6 monoclonal antibodyBovine
GM-Tg-equg-SE1378-Ab-1/ GM-Tg-equg-SE1378-Ab-2Anti-Equine WFDC6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1378-Ab-1/ GM-Tg-hg-SE1378-Ab-2; GM-Tg-rg-SE1378-Ab-1/ GM-Tg-rg-SE1378-Ab-2;
GM-Tg-mg-SE1378-Ab-1/ GM-Tg-mg-SE1378-Ab-2; GM-Tg-cynog-SE1378-Ab-1/ GM-Tg-cynog-SE1378-Ab-2;
GM-Tg-felg-SE1378-Ab-1/ GM-Tg-felg-SE1378-Ab-2; GM-Tg-cang-SE1378-Ab-1/ GM-Tg-cang-SE1378-Ab-2;
GM-Tg-bovg-SE1378-Ab-1/ GM-Tg-bovg-SE1378-Ab-2; GM-Tg-equg-SE1378-Ab-1/ GM-Tg-equg-SE1378-Ab-2
Products NameAnti-WFDC6 monoclonal antibody
Formatmab
Target NameWFDC6
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-WFDC6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1378-Ag-1Recombinant multi-species WFDC6/ C20orf171/ HEL-S-295 protein


    Target information

    Target IDGM-SE1378
    Target NameWFDC6
    Gene ID140870,100429080
    Gene Symbol and SynonymsC20orf171,dJ461P17.11,HEL-S-295,WAP6,WFDC6
    Uniprot AccessionQ9BQY6
    Uniprot Entry NameWFDC6_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000243543
    Target ClassificationN/A

    The target: WFDC6, gene name: WFDC6, also named as C20orf171, HEL-S-295, WAP6, dJ461P17.11. This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Read-through transcription exists between this gene and the upstream SPINLW1 (serine peptidase inhibitor-like, with Kunitz and WAP domains 1) gene. [provided by RefSeq, Nov 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.