Anti-WFDC6/ C20orf171/ HEL-S-295 functional antibody

Anti-WFDC6/ C20orf171/ HEL-S-295 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to WFDC6/WFDC6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1378-Ab-1/ GM-Tg-hg-SE1378-Ab-2Anti-Human WFDC6 monoclonal antibodyHuman
GM-Tg-rg-SE1378-Ab-1/ GM-Tg-rg-SE1378-Ab-2Anti-Rat WFDC6 monoclonal antibodyRat
GM-Tg-mg-SE1378-Ab-1/ GM-Tg-mg-SE1378-Ab-2Anti-Mouse WFDC6 monoclonal antibodyMouse
GM-Tg-cynog-SE1378-Ab-1/ GM-Tg-cynog-SE1378-Ab-2Anti-Cynomolgus/ Rhesus macaque WFDC6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1378-Ab-1/ GM-Tg-felg-SE1378-Ab-2Anti-Feline WFDC6 monoclonal antibodyFeline
GM-Tg-cang-SE1378-Ab-1/ GM-Tg-cang-SE1378-Ab-2Anti-Canine WFDC6 monoclonal antibodyCanine
GM-Tg-bovg-SE1378-Ab-1/ GM-Tg-bovg-SE1378-Ab-2Anti-Bovine WFDC6 monoclonal antibodyBovine
GM-Tg-equg-SE1378-Ab-1/ GM-Tg-equg-SE1378-Ab-2Anti-Equine WFDC6 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-SE1378-Ab-1/ GM-Tg-hg-SE1378-Ab-2; GM-Tg-rg-SE1378-Ab-1/ GM-Tg-rg-SE1378-Ab-2;
GM-Tg-mg-SE1378-Ab-1/ GM-Tg-mg-SE1378-Ab-2; GM-Tg-cynog-SE1378-Ab-1/ GM-Tg-cynog-SE1378-Ab-2;
GM-Tg-felg-SE1378-Ab-1/ GM-Tg-felg-SE1378-Ab-2; GM-Tg-cang-SE1378-Ab-1/ GM-Tg-cang-SE1378-Ab-2;
GM-Tg-bovg-SE1378-Ab-1/ GM-Tg-bovg-SE1378-Ab-2; GM-Tg-equg-SE1378-Ab-1/ GM-Tg-equg-SE1378-Ab-2
Products NameAnti-WFDC6 monoclonal antibody
Target NameWFDC6
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-WFDC6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1378-Ag-1Recombinant multi-species WFDC6/ C20orf171/ HEL-S-295 protein

    Target information

    Target IDGM-SE1378
    Target NameWFDC6
    Gene ID140870,100429080
    Gene Symbol and SynonymsC20orf171,dJ461P17.11,HEL-S-295,WAP6,WFDC6
    Uniprot AccessionQ9BQY6
    Uniprot Entry NameWFDC6_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Gene EnsemblENSG00000243543
    Target ClassificationN/A

    The target: WFDC6, gene name: WFDC6, also named as C20orf171, HEL-S-295, WAP6, dJ461P17.11. This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Read-through transcription exists between this gene and the upstream SPINLW1 (serine peptidase inhibitor-like, with Kunitz and WAP domains 1) gene. [provided by RefSeq, Nov 2010].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.