Anti-XCL2/ SCM-1b/ SCM1B functional antibody

Anti-XCL2/ SCM-1b/ SCM1B functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to XCL2/XCL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1387-Ab-1/ GM-Tg-hg-SE1387-Ab-2Anti-Human XCL2 monoclonal antibodyHuman
GM-Tg-rg-SE1387-Ab-1/ GM-Tg-rg-SE1387-Ab-2Anti-Rat XCL2 monoclonal antibodyRat
GM-Tg-mg-SE1387-Ab-1/ GM-Tg-mg-SE1387-Ab-2Anti-Mouse XCL2 monoclonal antibodyMouse
GM-Tg-cynog-SE1387-Ab-1/ GM-Tg-cynog-SE1387-Ab-2Anti-Cynomolgus/ Rhesus macaque XCL2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1387-Ab-1/ GM-Tg-felg-SE1387-Ab-2Anti-Feline XCL2 monoclonal antibodyFeline
GM-Tg-cang-SE1387-Ab-1/ GM-Tg-cang-SE1387-Ab-2Anti-Canine XCL2 monoclonal antibodyCanine
GM-Tg-bovg-SE1387-Ab-1/ GM-Tg-bovg-SE1387-Ab-2Anti-Bovine XCL2 monoclonal antibodyBovine
GM-Tg-equg-SE1387-Ab-1/ GM-Tg-equg-SE1387-Ab-2Anti-Equine XCL2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1387-Ab-1/ GM-Tg-hg-SE1387-Ab-2; GM-Tg-rg-SE1387-Ab-1/ GM-Tg-rg-SE1387-Ab-2;
GM-Tg-mg-SE1387-Ab-1/ GM-Tg-mg-SE1387-Ab-2; GM-Tg-cynog-SE1387-Ab-1/ GM-Tg-cynog-SE1387-Ab-2;
GM-Tg-felg-SE1387-Ab-1/ GM-Tg-felg-SE1387-Ab-2; GM-Tg-cang-SE1387-Ab-1/ GM-Tg-cang-SE1387-Ab-2;
GM-Tg-bovg-SE1387-Ab-1/ GM-Tg-bovg-SE1387-Ab-2; GM-Tg-equg-SE1387-Ab-1/ GM-Tg-equg-SE1387-Ab-2
Products NameAnti-XCL2 monoclonal antibody
Formatmab
Target NameXCL2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-XCL2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1387-Ag-1Recombinant multi-species XCL2/ SCM-1b/ SCM1B protein


    Target information

    Target IDGM-SE1387
    Target NameXCL2
    Gene ID6846
    Gene Symbol and SynonymsSCM-1b,SCM1B,SCYC2,XCL2
    Uniprot AccessionQ9UBD3
    Uniprot Entry NameXCL2_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000143185
    Target ClassificationN/A

    The target: XCL2, gene name: XCL2, also named as SCM-1b, SCM1B, SCYC2. Predicted to enable CCR chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; leukocyte chemotaxis; and positive regulation of T cell chemotaxis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.