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Anti-ANGE1/ ANGEL1/ Ccr4e functional antibody
Anti-ANGE1/ ANGEL1/ Ccr4e functional antibody for cell culture, ELISA & in-vivo assay
Go to ANGEL1/ANGEL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1402-Ab-1/ GM-Tg-hg-SE1402-Ab-2 | Anti-Human ANGEL1 monoclonal antibody | Human |
| GM-Tg-rg-SE1402-Ab-1/ GM-Tg-rg-SE1402-Ab-2 | Anti-Rat ANGEL1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1402-Ab-1/ GM-Tg-mg-SE1402-Ab-2 | Anti-Mouse ANGEL1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1402-Ab-1/ GM-Tg-cynog-SE1402-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ANGEL1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1402-Ab-1/ GM-Tg-felg-SE1402-Ab-2 | Anti-Feline ANGEL1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1402-Ab-1/ GM-Tg-cang-SE1402-Ab-2 | Anti-Canine ANGEL1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1402-Ab-1/ GM-Tg-bovg-SE1402-Ab-2 | Anti-Bovine ANGEL1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1402-Ab-1/ GM-Tg-equg-SE1402-Ab-2 | Anti-Equine ANGEL1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1402-Ab-1/ GM-Tg-hg-SE1402-Ab-2; GM-Tg-rg-SE1402-Ab-1/ GM-Tg-rg-SE1402-Ab-2; GM-Tg-mg-SE1402-Ab-1/ GM-Tg-mg-SE1402-Ab-2; GM-Tg-cynog-SE1402-Ab-1/ GM-Tg-cynog-SE1402-Ab-2; GM-Tg-felg-SE1402-Ab-1/ GM-Tg-felg-SE1402-Ab-2; GM-Tg-cang-SE1402-Ab-1/ GM-Tg-cang-SE1402-Ab-2; GM-Tg-bovg-SE1402-Ab-1/ GM-Tg-bovg-SE1402-Ab-2; GM-Tg-equg-SE1402-Ab-1/ GM-Tg-equg-SE1402-Ab-2 |
| Products Name | Anti-ANGEL1 monoclonal antibody |
| Format | mab |
| Target Name | ANGEL1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ANGEL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1402-Ag-1 | Recombinant multi-species ANGE1/ ANGEL1/ Ccr4e protein |
Target information
| Target ID | GM-SE1402 |
| Target Name | ANGEL1 |
| Gene ID | 23357,68737,362765,705043,490800,101084546,508197,100058855 |
| Gene Symbol and Synonyms | 1110030H02Rik,angel-like,ANGEL1,Ccr4e,KIAA0759,mKIAA0759,RGD1306238 |
| Uniprot Accession | Q9UNK9,B2RYM0 |
| Uniprot Entry Name | ANGE1_HUMAN,ANGE1_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000013523 |
| Target Classification | N/A |
The target: ANGEL1, gene name: ANGEL1, also named as Ccr4e, KIAA0759. Enables eukaryotic initiation factor 4E binding activity and protein domain specific binding activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, exonucleolytic. Located in several cellular components, including cis-Golgi network; endoplasmic reticulum; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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