Anti-ANGE1/ ANGEL1/ Ccr4e functional antibody

Anti-ANGE1/ ANGEL1/ Ccr4e functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ANGEL1/ANGEL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1402-Ab-1/ GM-Tg-hg-SE1402-Ab-2Anti-Human ANGEL1 monoclonal antibodyHuman
GM-Tg-rg-SE1402-Ab-1/ GM-Tg-rg-SE1402-Ab-2Anti-Rat ANGEL1 monoclonal antibodyRat
GM-Tg-mg-SE1402-Ab-1/ GM-Tg-mg-SE1402-Ab-2Anti-Mouse ANGEL1 monoclonal antibodyMouse
GM-Tg-cynog-SE1402-Ab-1/ GM-Tg-cynog-SE1402-Ab-2Anti-Cynomolgus/ Rhesus macaque ANGEL1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1402-Ab-1/ GM-Tg-felg-SE1402-Ab-2Anti-Feline ANGEL1 monoclonal antibodyFeline
GM-Tg-cang-SE1402-Ab-1/ GM-Tg-cang-SE1402-Ab-2Anti-Canine ANGEL1 monoclonal antibodyCanine
GM-Tg-bovg-SE1402-Ab-1/ GM-Tg-bovg-SE1402-Ab-2Anti-Bovine ANGEL1 monoclonal antibodyBovine
GM-Tg-equg-SE1402-Ab-1/ GM-Tg-equg-SE1402-Ab-2Anti-Equine ANGEL1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-SE1402-Ab-1/ GM-Tg-hg-SE1402-Ab-2; GM-Tg-rg-SE1402-Ab-1/ GM-Tg-rg-SE1402-Ab-2;
GM-Tg-mg-SE1402-Ab-1/ GM-Tg-mg-SE1402-Ab-2; GM-Tg-cynog-SE1402-Ab-1/ GM-Tg-cynog-SE1402-Ab-2;
GM-Tg-felg-SE1402-Ab-1/ GM-Tg-felg-SE1402-Ab-2; GM-Tg-cang-SE1402-Ab-1/ GM-Tg-cang-SE1402-Ab-2;
GM-Tg-bovg-SE1402-Ab-1/ GM-Tg-bovg-SE1402-Ab-2; GM-Tg-equg-SE1402-Ab-1/ GM-Tg-equg-SE1402-Ab-2
Products NameAnti-ANGEL1 monoclonal antibody
Target NameANGEL1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-ANGEL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1402-Ag-1Recombinant multi-species ANGE1/ ANGEL1/ Ccr4e protein

    Target information

    Target IDGM-SE1402
    Target NameANGEL1
    Gene ID23357,68737,362765,705043,490800,101084546,508197,100058855
    Gene Symbol and Synonyms1110030H02Rik,angel-like,ANGEL1,Ccr4e,KIAA0759,mKIAA0759,RGD1306238
    Uniprot AccessionQ9UNK9,B2RYM0
    Uniprot Entry NameANGE1_HUMAN,ANGE1_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Gene EnsemblENSG00000013523
    Target ClassificationN/A

    The target: ANGEL1, gene name: ANGEL1, also named as Ccr4e, KIAA0759. Enables eukaryotic initiation factor 4E binding activity and protein domain specific binding activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, exonucleolytic. Located in several cellular components, including cis-Golgi network; endoplasmic reticulum; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.