Anti-G6PE/ H6PD/ CORTRD1 functional antibody

Anti-G6PE/ H6PD/ CORTRD1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to H6PD/H6PD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1408-Ab-1/ GM-Tg-hg-SE1408-Ab-2Anti-Human H6PD monoclonal antibodyHuman
GM-Tg-rg-SE1408-Ab-1/ GM-Tg-rg-SE1408-Ab-2Anti-Rat H6PD monoclonal antibodyRat
GM-Tg-mg-SE1408-Ab-1/ GM-Tg-mg-SE1408-Ab-2Anti-Mouse H6PD monoclonal antibodyMouse
GM-Tg-cynog-SE1408-Ab-1/ GM-Tg-cynog-SE1408-Ab-2Anti-Cynomolgus/ Rhesus macaque H6PD monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1408-Ab-1/ GM-Tg-felg-SE1408-Ab-2Anti-Feline H6PD monoclonal antibodyFeline
GM-Tg-cang-SE1408-Ab-1/ GM-Tg-cang-SE1408-Ab-2Anti-Canine H6PD monoclonal antibodyCanine
GM-Tg-bovg-SE1408-Ab-1/ GM-Tg-bovg-SE1408-Ab-2Anti-Bovine H6PD monoclonal antibodyBovine
GM-Tg-equg-SE1408-Ab-1/ GM-Tg-equg-SE1408-Ab-2Anti-Equine H6PD monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1408-Ab-1/ GM-Tg-hg-SE1408-Ab-2; GM-Tg-rg-SE1408-Ab-1/ GM-Tg-rg-SE1408-Ab-2;
GM-Tg-mg-SE1408-Ab-1/ GM-Tg-mg-SE1408-Ab-2; GM-Tg-cynog-SE1408-Ab-1/ GM-Tg-cynog-SE1408-Ab-2;
GM-Tg-felg-SE1408-Ab-1/ GM-Tg-felg-SE1408-Ab-2; GM-Tg-cang-SE1408-Ab-1/ GM-Tg-cang-SE1408-Ab-2;
GM-Tg-bovg-SE1408-Ab-1/ GM-Tg-bovg-SE1408-Ab-2; GM-Tg-equg-SE1408-Ab-1/ GM-Tg-equg-SE1408-Ab-2
Products NameAnti-H6PD monoclonal antibody
Formatmab
Target NameH6PD
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-H6PD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1408-Ag-1Recombinant multi-species G6PE/ H6PD/ CORTRD1 protein


    Target information

    Target IDGM-SE1408
    Target NameH6PD
    Gene ID9563,100198,298655,710107,489642,101098066,100057646
    Gene Symbol and SynonymsCORTRD1,G6pd1,G6PDH,GDH,Gpd-1,Gpd1,H6PD,H6PDH
    Uniprot AccessionO95479
    Uniprot Entry NameG6PE_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000049239
    Target ClassificationN/A

    The target: H6PD, gene name: H6PD, also named as CORTRD1, G6PDH, GDH. There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells. [provided by RefSeq, Jul 2008].



    About Gmab

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s TaurusTM and LIBRATM platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.