Anti-ADPRS/ ADPRHL2/ ARH3 functional antibody

Anti-ADPRS/ ADPRHL2/ ARH3 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ADPRHL2/ADPRHL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1469-Ab-1/ GM-Tg-hg-SE1469-Ab-2Anti-Human ADPRHL2 monoclonal antibodyHuman
GM-Tg-rg-SE1469-Ab-1/ GM-Tg-rg-SE1469-Ab-2Anti-Rat ADPRHL2 monoclonal antibodyRat
GM-Tg-mg-SE1469-Ab-1/ GM-Tg-mg-SE1469-Ab-2Anti-Mouse ADPRHL2 monoclonal antibodyMouse
GM-Tg-cynog-SE1469-Ab-1/ GM-Tg-cynog-SE1469-Ab-2Anti-Cynomolgus/ Rhesus macaque ADPRHL2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1469-Ab-1/ GM-Tg-felg-SE1469-Ab-2Anti-Feline ADPRHL2 monoclonal antibodyFeline
GM-Tg-cang-SE1469-Ab-1/ GM-Tg-cang-SE1469-Ab-2Anti-Canine ADPRHL2 monoclonal antibodyCanine
GM-Tg-bovg-SE1469-Ab-1/ GM-Tg-bovg-SE1469-Ab-2Anti-Bovine ADPRHL2 monoclonal antibodyBovine
GM-Tg-equg-SE1469-Ab-1/ GM-Tg-equg-SE1469-Ab-2Anti-Equine ADPRHL2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1469-Ab-1/ GM-Tg-hg-SE1469-Ab-2; GM-Tg-rg-SE1469-Ab-1/ GM-Tg-rg-SE1469-Ab-2;
GM-Tg-mg-SE1469-Ab-1/ GM-Tg-mg-SE1469-Ab-2; GM-Tg-cynog-SE1469-Ab-1/ GM-Tg-cynog-SE1469-Ab-2;
GM-Tg-felg-SE1469-Ab-1/ GM-Tg-felg-SE1469-Ab-2; GM-Tg-cang-SE1469-Ab-1/ GM-Tg-cang-SE1469-Ab-2;
GM-Tg-bovg-SE1469-Ab-1/ GM-Tg-bovg-SE1469-Ab-2; GM-Tg-equg-SE1469-Ab-1/ GM-Tg-equg-SE1469-Ab-2
Products NameAnti-ADPRHL2 monoclonal antibody
Formatmab
Target NameADPRHL2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ADPRHL2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1469-Ag-1Recombinant multi-species ADPRS/ ADPRHL2/ ARH3 protein


    Target information

    Target IDGM-SE1469
    Target NameADPRHL2
    Gene ID54936,100206,362600,712758,608601,101086825,521650,100069360
    Gene Symbol and SynonymsADPRHL2,ADPRS,ARH3,CONDSIAS
    Uniprot AccessionQ9NX46,Q3SYV9
    Uniprot Entry NameADPRS_HUMAN,ADPRS_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000116863
    Target ClassificationN/A

    The target: ADPRHL2, gene name: ADPRHL2, also named as ARH3. This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm.[provided by RefSeq, Feb 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.