Anti-SDF2 functional antibody

Anti-SDF2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SDF2/SDF2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1498-Ab-1/ GM-Tg-hg-SE1498-Ab-2Anti-Human SDF2 monoclonal antibodyHuman
GM-Tg-rg-SE1498-Ab-1/ GM-Tg-rg-SE1498-Ab-2Anti-Rat SDF2 monoclonal antibodyRat
GM-Tg-mg-SE1498-Ab-1/ GM-Tg-mg-SE1498-Ab-2Anti-Mouse SDF2 monoclonal antibodyMouse
GM-Tg-cynog-SE1498-Ab-1/ GM-Tg-cynog-SE1498-Ab-2Anti-Cynomolgus/ Rhesus macaque SDF2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1498-Ab-1/ GM-Tg-felg-SE1498-Ab-2Anti-Feline SDF2 monoclonal antibodyFeline
GM-Tg-cang-SE1498-Ab-1/ GM-Tg-cang-SE1498-Ab-2Anti-Canine SDF2 monoclonal antibodyCanine
GM-Tg-bovg-SE1498-Ab-1/ GM-Tg-bovg-SE1498-Ab-2Anti-Bovine SDF2 monoclonal antibodyBovine
GM-Tg-equg-SE1498-Ab-1/ GM-Tg-equg-SE1498-Ab-2Anti-Equine SDF2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1498-Ab-1/ GM-Tg-hg-SE1498-Ab-2; GM-Tg-rg-SE1498-Ab-1/ GM-Tg-rg-SE1498-Ab-2;
GM-Tg-mg-SE1498-Ab-1/ GM-Tg-mg-SE1498-Ab-2; GM-Tg-cynog-SE1498-Ab-1/ GM-Tg-cynog-SE1498-Ab-2;
GM-Tg-felg-SE1498-Ab-1/ GM-Tg-felg-SE1498-Ab-2; GM-Tg-cang-SE1498-Ab-1/ GM-Tg-cang-SE1498-Ab-2;
GM-Tg-bovg-SE1498-Ab-1/ GM-Tg-bovg-SE1498-Ab-2; GM-Tg-equg-SE1498-Ab-1/ GM-Tg-equg-SE1498-Ab-2
Products NameAnti-SDF2 monoclonal antibody
Formatmab
Target NameSDF2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SDF2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1498-Ag-1Recombinant multi-species SDF2 protein
    ORF Viral VectorvGMLP000385human SDF2 Lentivirus particle
    ORF Viral VectorpGMLP000385human SDF2 Lentivirus plasmid


    Target information

    Target IDGM-SE1498
    Target NameSDF2
    Gene ID6388,20316,287470,716189,480626,101098096,508463,100059307
    Gene Symbol and SynonymsSDF2
    Uniprot AccessionQ99470,Q3SZ45
    Uniprot Entry NameSDF2_HUMAN,SDF2_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000132581
    Target ClassificationN/A

    The target: SDF2, gene name: SDF2, also named as . The protein encoded by this gene is believed to be a secretory protein. It has regions of similarity to hydrophilic segments of yeast mannosyltransferases. Its expression is ubiquitous and the gene appears to be relatively conserved among mammals. Alternate splicing results in both coding and non-coding variants. A pseudogene of this gene is located on chromosome 15. [provided by RefSeq, Dec 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.