Anti-GL6D1/ GLT6D1/ GLTDC1 functional antibody

Anti-GL6D1/ GLT6D1/ GLTDC1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to GLT6D1/GLT6D1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1652-Ab-1/ GM-Tg-hg-SE1652-Ab-2Anti-Human GLT6D1 monoclonal antibodyHuman
GM-Tg-rg-SE1652-Ab-1/ GM-Tg-rg-SE1652-Ab-2Anti-Rat GLT6D1 monoclonal antibodyRat
GM-Tg-mg-SE1652-Ab-1/ GM-Tg-mg-SE1652-Ab-2Anti-Mouse GLT6D1 monoclonal antibodyMouse
GM-Tg-cynog-SE1652-Ab-1/ GM-Tg-cynog-SE1652-Ab-2Anti-Cynomolgus/ Rhesus macaque GLT6D1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1652-Ab-1/ GM-Tg-felg-SE1652-Ab-2Anti-Feline GLT6D1 monoclonal antibodyFeline
GM-Tg-cang-SE1652-Ab-1/ GM-Tg-cang-SE1652-Ab-2Anti-Canine GLT6D1 monoclonal antibodyCanine
GM-Tg-bovg-SE1652-Ab-1/ GM-Tg-bovg-SE1652-Ab-2Anti-Bovine GLT6D1 monoclonal antibodyBovine
GM-Tg-equg-SE1652-Ab-1/ GM-Tg-equg-SE1652-Ab-2Anti-Equine GLT6D1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1652-Ab-1/ GM-Tg-hg-SE1652-Ab-2; GM-Tg-rg-SE1652-Ab-1/ GM-Tg-rg-SE1652-Ab-2;
GM-Tg-mg-SE1652-Ab-1/ GM-Tg-mg-SE1652-Ab-2; GM-Tg-cynog-SE1652-Ab-1/ GM-Tg-cynog-SE1652-Ab-2;
GM-Tg-felg-SE1652-Ab-1/ GM-Tg-felg-SE1652-Ab-2; GM-Tg-cang-SE1652-Ab-1/ GM-Tg-cang-SE1652-Ab-2;
GM-Tg-bovg-SE1652-Ab-1/ GM-Tg-bovg-SE1652-Ab-2; GM-Tg-equg-SE1652-Ab-1/ GM-Tg-equg-SE1652-Ab-2
Products NameAnti-GLT6D1 monoclonal antibody
Formatmab
Target NameGLT6D1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GLT6D1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1652-Ag-1Recombinant multi-species GL6D1/ GLT6D1/ GLTDC1 protein


    Target information

    Target IDGM-SE1652
    Target NameGLT6D1
    Gene ID360203,71103,296577,711729,491262,101090658,529958,100068354
    Gene Symbol and Synonyms4933411C14Rik,GLT6D1,GLTDC1,GT6M7
    Uniprot AccessionQ7Z4J2,D3ZNQ3,Q2YDM8
    Uniprot Entry NameGL6D1_HUMAN,GL6D1_RAT,GL6D1_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000204007
    Target ClassificationN/A

    The target: GLT6D1, gene name: GLT6D1, also named as GLTDC1, GT6M7. The GT6 glycosyltransferases gene family, which includes the ABO blood group (ABO; MIM 110300) and GLT6D1, shows a complex evolution pattern, with multiple events of gain and loss in different mammal species. In humans, the ABO gene is considered the sole functional member, although the O allele is null and is fixed in certain populations (summary by Casals et al. (2009) [PubMed 19218399]).[supplied by OMIM, Jan 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.