Anti-ABCC9/ ABC37/ ATFB12 antibody for FACS & in-vivo assay| GMab

Pre-made anti-ABCC9 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ABCC9 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

The target: ABCC9, gene name: ABCC9, also named as ABC37, ATFB12, CANTU, CMD1O, SUR2. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011].

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Catalog No.	List Price (In USD)	Discount Price (In USD)	Qty (Quantity)	Sum (In USD)
GM-Tg-hg-T02777-Ab-1-1mg	5150	3090
GM-Tg-hg-T02777-Ab-1-10mg	Inquiry	Inquiry
GM-Tg-hg-T02777-Ab-1-100mg	Inquiry	Inquiry
GM-Tg-hg-T02777-Ab-2-1mg	5150	3090
GM-Tg-hg-T02777-Ab-2-10mg	Inquiry	Inquiry
GM-Tg-hg-T02777-Ab-2-100mg	Inquiry	Inquiry
GM-Tg-hg-T02777-Ab-xmg	Inquiry	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Catalog No.	GM-Tg-hg-T02777-Ab-1, GM-Tg-hg-T02777-Ab-2
Products Name	Anti-ABCC9 monoclonal antibody
Format	mab
Target Name	ABCC9
Gene ID	ABCC9
Gene Name	ABCC9
Gene Alias	ABC37, ATFB12, CANTU, CMD1O, SUR2
Protein Sub-location	Transmembrane Protein
Category of antibody	FACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)	Mouse
Species Reactivity	Human(H)
CH1+2+3 Isotype (Receptor identification)	IgG
Type of Light Chain (VD-LC)	N/A
Expression platform	Mammalian Expression
Bioactivity validation	Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Tag	Fc
Products description	Pre-made anti-ABCC9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity	Purity: ≥95% (SDS-PAGE)
Application	Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.