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Anti-ABCC9/ ABC37/ ATFB12 monoclonal antibody
Anti-ABCC9/ ABC37/ ATFB12 antibody for FACS & in-vivo assay
Go to ABCC9/ABCC9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T02777-Ab-1/ GM-Tg-hg-T02777-Ab-2 | Anti-Human ABCC9 monoclonal antibody | Human |
| GM-Tg-rg-T02777-Ab-1/ GM-Tg-rg-T02777-Ab-2 | Anti-Rat ABCC9 monoclonal antibody | Rat |
| GM-Tg-mg-T02777-Ab-1/ GM-Tg-mg-T02777-Ab-2 | Anti-Mouse ABCC9 monoclonal antibody | Mouse |
| GM-Tg-cynog-T02777-Ab-1/ GM-Tg-cynog-T02777-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ABCC9 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T02777-Ab-1/ GM-Tg-felg-T02777-Ab-2 | Anti-Feline ABCC9 monoclonal antibody | Feline |
| GM-Tg-cang-T02777-Ab-1/ GM-Tg-cang-T02777-Ab-2 | Anti-Canine ABCC9 monoclonal antibody | Canine |
| GM-Tg-bovg-T02777-Ab-1/ GM-Tg-bovg-T02777-Ab-2 | Anti-Bovine ABCC9 monoclonal antibody | Bovine |
| GM-Tg-equg-T02777-Ab-1/ GM-Tg-equg-T02777-Ab-2 | Anti-Equine ABCC9 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T02777-Ab-1/ GM-Tg-hg-T02777-Ab-2; GM-Tg-rg-T02777-Ab-1/ GM-Tg-rg-T02777-Ab-2; GM-Tg-mg-T02777-Ab-1/ GM-Tg-mg-T02777-Ab-2; GM-Tg-cynog-T02777-Ab-1/ GM-Tg-cynog-T02777-Ab-2; GM-Tg-felg-T02777-Ab-1/ GM-Tg-felg-T02777-Ab-2; GM-Tg-cang-T02777-Ab-1/ GM-Tg-cang-T02777-Ab-2; GM-Tg-bovg-T02777-Ab-1/ GM-Tg-bovg-T02777-Ab-2; GM-Tg-equg-T02777-Ab-1/ GM-Tg-equg-T02777-Ab-2 |
| Products Name | Anti-ABCC9 monoclonal antibody |
| Format | mab |
| Target Name | ABCC9 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ABCC9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ABCC9/ ABC37/ ATFB12 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-T02777 |
| Target Name | ABCC9 |
| Gene ID | 10060,20928,25560,654489,486638,101096657,100336551,111767477 |
| Gene Symbol and Synonyms | ABC37,ABCC9,ATFB12,CANTU,CMD1O,IDMYS,SUR2,SUR2A,SUR2B |
| Uniprot Accession | O60706,Q63563 |
| Uniprot Entry Name | ABCC9_HUMAN,ABCC9_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000069431 |
| Target Classification | N/A |
The target: ABCC9, gene name: ABCC9, also named as ABC37, ATFB12, CANTU, CMD1O, SUR2. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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