
Pre-made anti-mKRAS monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.
Cat No.: GM-Tg-hg-T03046-Ab
Pre-made anti-mKRAS monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-mKRAS mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: mKRAS, gene name: KRAS, also named as C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, KI-RAS1, KRAS2, NS, NS3, RALD, RASK2, c-Ki-ras2, KRAS. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008].
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Catalog No. | List Price (In USD) | Discount Price (In USD) | Qty (Quantity) | Sum (In USD) |
---|---|---|---|---|
GM-Tg-hg-T03046-Ab-1-1mg | 5150 | 3090 | ||
GM-Tg-hg-T03046-Ab-1-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-T03046-Ab-1-100mg | Inquiry | Inquiry | GM-Tg-hg-T03046-Ab-2-1mg | 5150 | 3090 |
GM-Tg-hg-T03046-Ab-2-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-T03046-Ab-2-100mg | Inquiry | Inquiry | GM-Tg-hg-T03046-Ab-xmg | Inquiry | Inquiry |
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Catalog No. | GM-Tg-hg-T03046-Ab-1, GM-Tg-hg-T03046-Ab-2 |
Products Name | Anti-mKRAS/KRAS monoclonal antibody |
Format | mab |
Target Name | mKRAS |
Gene ID | KRAS |
Gene Name | KRAS |
Gene Alias | C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, KI-RAS1, KRAS2, NS, NS3, RALD, RASK2, c-Ki-ras2, KRAS |
Protein Sub-location | Introcelluar Protein |
Category of antibody | Therapeutics Target antibody |
Derivation (species) | Mouse |
Species Reactivity | Human(H) |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-mKRAS monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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