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Anti-CCL20/ CKb4/ Exodus functional antibody
Anti-CCL20/ CKb4/ Exodus functional antibody for cell culture, ELISA & in-vivo assay
Go to CCL20/CCL20 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T04894-Ab-1/ GM-Tg-hg-T04894-Ab-2 | Anti-Human CCL20 monoclonal antibody | Human |
| GM-Tg-rg-T04894-Ab-1/ GM-Tg-rg-T04894-Ab-2 | Anti-Rat CCL20 monoclonal antibody | Rat |
| GM-Tg-mg-T04894-Ab-1/ GM-Tg-mg-T04894-Ab-2 | Anti-Mouse CCL20 monoclonal antibody | Mouse |
| GM-Tg-cynog-T04894-Ab-1/ GM-Tg-cynog-T04894-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCL20 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T04894-Ab-1/ GM-Tg-felg-T04894-Ab-2 | Anti-Feline CCL20 monoclonal antibody | Feline |
| GM-Tg-cang-T04894-Ab-1/ GM-Tg-cang-T04894-Ab-2 | Anti-Canine CCL20 monoclonal antibody | Canine |
| GM-Tg-bovg-T04894-Ab-1/ GM-Tg-bovg-T04894-Ab-2 | Anti-Bovine CCL20 monoclonal antibody | Bovine |
| GM-Tg-equg-T04894-Ab-1/ GM-Tg-equg-T04894-Ab-2 | Anti-Equine CCL20 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T04894-Ab-1/ GM-Tg-hg-T04894-Ab-2; GM-Tg-rg-T04894-Ab-1/ GM-Tg-rg-T04894-Ab-2; GM-Tg-mg-T04894-Ab-1/ GM-Tg-mg-T04894-Ab-2; GM-Tg-cynog-T04894-Ab-1/ GM-Tg-cynog-T04894-Ab-2; GM-Tg-felg-T04894-Ab-1/ GM-Tg-felg-T04894-Ab-2; GM-Tg-cang-T04894-Ab-1/ GM-Tg-cang-T04894-Ab-2; GM-Tg-bovg-T04894-Ab-1/ GM-Tg-bovg-T04894-Ab-2; GM-Tg-equg-T04894-Ab-1/ GM-Tg-equg-T04894-Ab-2 |
| Products Name | Anti-CCL20 monoclonal antibody |
| Format | mab |
| Target Name | CCL20 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCL20 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T04894-Ag-1 | Recombinant multi-species CCL20/ CKb4/ Exodus protein |
| Cytokine | GM-Tg-g-T04894-Ag-1 | chemokine (C-C motif) ligand 20 (CCL20) protein |
| ORF Viral Vector | vGMLV000235 | human CCL20 Lentivirus particle |
| ORF Viral Vector | pGMLV000235 | human CCL20 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000006 | mouse Ccl20 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000006 | mouse Ccl20 Lentivirus particle |
Target information
| Target ID | GM-T04894 |
| Target Name | CCL20 |
| Gene ID | 6364,20297,29538,574182,448790,101089032,281666,100629808 |
| Gene Symbol and Synonyms | CCL20,CKb4,Exodus,exodus-1,LARC,MIP-3-alpha,MIP-3a,MIP-3[a],MIP3A,SCYA20,ST38 |
| Uniprot Accession | P78556,P97884,Q8SQB1 |
| Uniprot Entry Name | CCL20_HUMAN,CCL20_RAT,CCL20_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Immuno-oncology Target, Cytokine Target |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000115009 |
| Target Classification | Checkpoint-Immuno Oncology |
The target: CCL20, gene name: CCL20, also named as CKb4, Exodus, LARC, MIP-3-alpha, MIP-3a, MIP3A, SCYA20, ST38. This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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