Anti-CCR4/ CC-CKR-4/ CD194 antibody for FACS & in-vivo assay| GMab

Pre-made anti-CCR4 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CCR4 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

The target: CCR4, gene name: CCR4, also named as CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5. The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008].

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Catalog No.	List Price (In USD)	Discount Price (In USD)	Qty (Quantity)	Sum (In USD)
GM-Tg-hg-T06955-Ab-1-1mg	5150	3090
GM-Tg-hg-T06955-Ab-1-10mg	Inquiry	Inquiry
GM-Tg-hg-T06955-Ab-1-100mg	Inquiry	Inquiry
GM-Tg-hg-T06955-Ab-2-1mg	5150	3090
GM-Tg-hg-T06955-Ab-2-10mg	Inquiry	Inquiry
GM-Tg-hg-T06955-Ab-2-100mg	Inquiry	Inquiry
GM-Tg-hg-T06955-Ab-xmg	Inquiry	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Catalog No.	GM-Tg-hg-T06955-Ab-1, GM-Tg-hg-T06955-Ab-2
Products Name	Anti-CCR4 monoclonal antibody
Format	mab
Target Name	CCR4
Gene ID	CCR4
Gene Name	CCR4
Gene Alias	CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5
Protein Sub-location	Transmembrane Protein
Category of antibody	FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)	Mouse
Species Reactivity	Human(H)
CH1+2+3 Isotype (Receptor identification)	IgG
Type of Light Chain (VD-LC)	N/A
Expression platform	Mammalian Expression
Bioactivity validation	Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Tag	Fc
Products description	Pre-made anti-CCR4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity	Purity: ≥95% (SDS-PAGE)
Application	Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.