Anti-CCR4/ CC-CKR-4/ CD194 monoclonal antibody

Anti-CCR4/ CC-CKR-4/ CD194 antibody for FACS & in-vivo assay

Target products collectionGo to CCR4/CCR4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T06955-Ab-1/ GM-Tg-hg-T06955-Ab-2Anti-Human CCR4 monoclonal antibodyHuman
GM-Tg-rg-T06955-Ab-1/ GM-Tg-rg-T06955-Ab-2Anti-Rat CCR4 monoclonal antibodyRat
GM-Tg-mg-T06955-Ab-1/ GM-Tg-mg-T06955-Ab-2Anti-Mouse CCR4 monoclonal antibodyMouse
GM-Tg-cynog-T06955-Ab-1/ GM-Tg-cynog-T06955-Ab-2Anti-Cynomolgus/ Rhesus macaque CCR4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T06955-Ab-1/ GM-Tg-felg-T06955-Ab-2Anti-Feline CCR4 monoclonal antibodyFeline
GM-Tg-cang-T06955-Ab-1/ GM-Tg-cang-T06955-Ab-2Anti-Canine CCR4 monoclonal antibodyCanine
GM-Tg-bovg-T06955-Ab-1/ GM-Tg-bovg-T06955-Ab-2Anti-Bovine CCR4 monoclonal antibodyBovine
GM-Tg-equg-T06955-Ab-1/ GM-Tg-equg-T06955-Ab-2Anti-Equine CCR4 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T06955-Ab-1/ GM-Tg-hg-T06955-Ab-2; GM-Tg-rg-T06955-Ab-1/ GM-Tg-rg-T06955-Ab-2;
GM-Tg-mg-T06955-Ab-1/ GM-Tg-mg-T06955-Ab-2; GM-Tg-cynog-T06955-Ab-1/ GM-Tg-cynog-T06955-Ab-2;
GM-Tg-felg-T06955-Ab-1/ GM-Tg-felg-T06955-Ab-2; GM-Tg-cang-T06955-Ab-1/ GM-Tg-cang-T06955-Ab-2;
GM-Tg-bovg-T06955-Ab-1/ GM-Tg-bovg-T06955-Ab-2; GM-Tg-equg-T06955-Ab-1/ GM-Tg-equg-T06955-Ab-2
Products NameAnti-CCR4 monoclonal antibody
Target NameCCR4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-CCR4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

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    Associated products

    CategoryCat No.Products Name
    BiosimilarGMP-Bios-ab-354Pre-Made Mogamulizumab biosimilar, Whole mAb, Anti-CCR4 Antibody: Anti-CKR4/K5-5/CD194/CMKBR4/ChemR13/CC-CKR-4/HGCN:14099 therapeutic antibody
    Target AntigenProducts DevelopingMulti-species CCR4/ CC-CKR-4/ CD194 VLP (virus-like particle) (Products Developing)
    CytokineGM-Tg-g-T06955-Ag-1chemokine (C-C motif) receptor 4 (CCR4) protein
    ORF Viral VectorvGMLP002020human CCR4 Lentivirus particle
    ORF Viral VectorpGMLP002020human CCR4 Lentivirus plasmid
    ORF Viral VectorpGMLV000154mouse Ccr4 Lentivirus plasmid
    ORF Viral VectorvGMLV000154mouse Ccr4 Lentivirus particle

    Target information

    Target IDGM-T06955
    Target NameCCR4
    Gene ID1233,12773,171054,705457,403541,102900629,408019,100056549
    Gene Symbol and SynonymsC-C CKR-4,CC-CKR-4,CCR4,CD194,CHEMR1,ChemR13,CKR4,CMKBR4,HGCN:14099,K5-5,LESTR,Sdf1r
    Uniprot AccessionP51679,Q8MJW8
    Uniprot Entry NameCCR4_HUMAN,CCR4_CANLF
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
    Gene EnsemblENSG00000183813
    Target ClassificationCheckpoint-Immuno Oncology, GPCR, Tumor-associated antigen (TAA)

    The target: CCR4, gene name: CCR4, also named as CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5. The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.