Anti-ACKR1/ CCBP1/ CD234 monoclonal antibody

Anti-ACKR1/ CCBP1/ CD234 antibody for FACS & in-vivo assay

Target products collectionGo to ACKR1/ACKR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T07289-Ab-1/ GM-Tg-hg-T07289-Ab-2Anti-Human ACKR1 monoclonal antibodyHuman
GM-Tg-rg-T07289-Ab-1/ GM-Tg-rg-T07289-Ab-2Anti-Rat ACKR1 monoclonal antibodyRat
GM-Tg-mg-T07289-Ab-1/ GM-Tg-mg-T07289-Ab-2Anti-Mouse ACKR1 monoclonal antibodyMouse
GM-Tg-cynog-T07289-Ab-1/ GM-Tg-cynog-T07289-Ab-2Anti-Cynomolgus/ Rhesus macaque ACKR1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T07289-Ab-1/ GM-Tg-felg-T07289-Ab-2Anti-Feline ACKR1 monoclonal antibodyFeline
GM-Tg-cang-T07289-Ab-1/ GM-Tg-cang-T07289-Ab-2Anti-Canine ACKR1 monoclonal antibodyCanine
GM-Tg-bovg-T07289-Ab-1/ GM-Tg-bovg-T07289-Ab-2Anti-Bovine ACKR1 monoclonal antibodyBovine
GM-Tg-equg-T07289-Ab-1/ GM-Tg-equg-T07289-Ab-2Anti-Equine ACKR1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T07289-Ab-1/ GM-Tg-hg-T07289-Ab-2; GM-Tg-rg-T07289-Ab-1/ GM-Tg-rg-T07289-Ab-2;
GM-Tg-mg-T07289-Ab-1/ GM-Tg-mg-T07289-Ab-2; GM-Tg-cynog-T07289-Ab-1/ GM-Tg-cynog-T07289-Ab-2;
GM-Tg-felg-T07289-Ab-1/ GM-Tg-felg-T07289-Ab-2; GM-Tg-cang-T07289-Ab-1/ GM-Tg-cang-T07289-Ab-2;
GM-Tg-bovg-T07289-Ab-1/ GM-Tg-bovg-T07289-Ab-2; GM-Tg-equg-T07289-Ab-1/ GM-Tg-equg-T07289-Ab-2
Products NameAnti-ACKR1 monoclonal antibody
Formatmab
Target NameACKR1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ACKR1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ACKR1/ CCBP1/ CD234 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T07289
    Target NameACKR1
    Gene ID2532,13349,689105,719284,100856110,101094569,528076,100057225
    Gene Symbol and SynonymsACKR1,CCBP1,CD234,DARC,DARC/ACKR1,Dfy,ES™35,FY,GPD,GpFy,WBCQ1
    Uniprot AccessionQ16570,Q95LF2,Q9GLX0
    Uniprot Entry NameACKR1_HUMAN,ACKR1_MACMU,ACKR1_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000213088
    Target ClassificationN/A

    The target: ACKR1, gene name: ACKR1, also named as CCBP1, CD234, DARC, DARC/ACKR1, Dfy, FY, GPD, GpFy, WBCQ1. The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.