Anti-ALDH5A1 monoclonal antibody

Pre-made anti-ALDH5A1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ALDH5A1/ALDH5A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T13259-Ab-1/ GM-Tg-hg-T13259-Ab-2Anti-Human ALDH5A1 monoclonal antibodyHuman
GM-Tg-rg-T13259-Ab-1/ GM-Tg-rg-T13259-Ab-2Anti-Rat ALDH5A1 monoclonal antibodyRat
GM-Tg-mg-T13259-Ab-1/ GM-Tg-mg-T13259-Ab-2Anti-Mouse ALDH5A1 monoclonal antibodyMouse
GM-Tg-cynog-T13259-Ab-1/ GM-Tg-cynog-T13259-Ab-2Anti-Cynomolgus/ Rhesus macaque ALDH5A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T13259-Ab-1/ GM-Tg-felg-T13259-Ab-2Anti-Feline ALDH5A1 monoclonal antibodyFeline
GM-Tg-cang-T13259-Ab-1/ GM-Tg-cang-T13259-Ab-2Anti-Canine ALDH5A1 monoclonal antibodyCanine
GM-Tg-bovg-T13259-Ab-1/ GM-Tg-bovg-T13259-Ab-2Anti-Bovine ALDH5A1 monoclonal antibodyBovine
GM-Tg-equg-T13259-Ab-1/ GM-Tg-equg-T13259-Ab-2Anti-Equine ALDH5A1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T13259-Ab-1/ GM-Tg-hg-T13259-Ab-2; GM-Tg-rg-T13259-Ab-1/ GM-Tg-rg-T13259-Ab-2;
GM-Tg-mg-T13259-Ab-1/ GM-Tg-mg-T13259-Ab-2; GM-Tg-cynog-T13259-Ab-1/ GM-Tg-cynog-T13259-Ab-2;
GM-Tg-felg-T13259-Ab-1/ GM-Tg-felg-T13259-Ab-2; GM-Tg-cang-T13259-Ab-1/ GM-Tg-cang-T13259-Ab-2;
GM-Tg-bovg-T13259-Ab-1/ GM-Tg-bovg-T13259-Ab-2; GM-Tg-equg-T13259-Ab-1/ GM-Tg-equg-T13259-Ab-2
Products NameAnti-ALDH5A1 monoclonal antibody
Formatmab
Target NameALDH5A1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-ALDH5A1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T13259-Ag-1Recombinant multi-species SSDH/ ALDH5A1/ SSADH protein


    Target information

    Target IDGM-T13259
    Target NameALDH5A1
    Gene ID7915,214579,291133,707902,488246,101088238,532724,100067559
    Gene Symbol and Synonyms6330403E24Rik,Ahd-1,Ahd1,ALDH5A1,D630032B01Rik,SSADH,SSDH,Ssdh1
    Uniprot AccessionP51649,P51650
    Uniprot Entry NameSSDH_HUMAN,SSDH_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000112294
    Target ClassificationN/A

    The target: ALDH5A1, gene name: ALDH5A1, also named as SSADH, SSDH. This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.