Anti-SSR3/ SSTR3/ SS-3-R monoclonal antibody

Anti-SSR3/ SSTR3/ SS-3-R antibody for FACS & in-vivo assay

Target products collectionGo to SSTR3/SSTR3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T13644-Ab-1/ GM-Tg-hg-T13644-Ab-2Anti-Human SSTR3 monoclonal antibodyHuman
GM-Tg-rg-T13644-Ab-1/ GM-Tg-rg-T13644-Ab-2Anti-Rat SSTR3 monoclonal antibodyRat
GM-Tg-mg-T13644-Ab-1/ GM-Tg-mg-T13644-Ab-2Anti-Mouse SSTR3 monoclonal antibodyMouse
GM-Tg-cynog-T13644-Ab-1/ GM-Tg-cynog-T13644-Ab-2Anti-Cynomolgus/ Rhesus macaque SSTR3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T13644-Ab-1/ GM-Tg-felg-T13644-Ab-2Anti-Feline SSTR3 monoclonal antibodyFeline
GM-Tg-cang-T13644-Ab-1/ GM-Tg-cang-T13644-Ab-2Anti-Canine SSTR3 monoclonal antibodyCanine
GM-Tg-bovg-T13644-Ab-1/ GM-Tg-bovg-T13644-Ab-2Anti-Bovine SSTR3 monoclonal antibodyBovine
GM-Tg-equg-T13644-Ab-1/ GM-Tg-equg-T13644-Ab-2Anti-Equine SSTR3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T13644-Ab-1/ GM-Tg-hg-T13644-Ab-2; GM-Tg-rg-T13644-Ab-1/ GM-Tg-rg-T13644-Ab-2;
GM-Tg-mg-T13644-Ab-1/ GM-Tg-mg-T13644-Ab-2; GM-Tg-cynog-T13644-Ab-1/ GM-Tg-cynog-T13644-Ab-2;
GM-Tg-felg-T13644-Ab-1/ GM-Tg-felg-T13644-Ab-2; GM-Tg-cang-T13644-Ab-1/ GM-Tg-cang-T13644-Ab-2;
GM-Tg-bovg-T13644-Ab-1/ GM-Tg-bovg-T13644-Ab-2; GM-Tg-equg-T13644-Ab-1/ GM-Tg-equg-T13644-Ab-2
Products NameAnti-SSTR3 monoclonal antibody
Formatmab
Target NameSSTR3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SSTR3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SSR3/ SSTR3/ SS-3-R VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP003671human SSTR3 Lentivirus particle
    ORF Viral VectorpGMLP003671human SSTR3 Lentivirus plasmid
    ORF Viral VectorpGMLPm004364mouse Sstr3 Lentivirus plasmid
    ORF Viral VectorvGMLPm004364mouse Sstr3 Lentivirus particle


    Target information

    Target IDGM-T13644
    Target NameSSTR3
    Gene ID6753,20607,171044,696585,481272,101096494,518585,100069706
    Gene Symbol and SynonymsSmstr-3,Smstr28,Smstr3,SS-3-R,SS3-R,SS3R,SSR-28,SST3,SSTR,SSTR3
    Uniprot AccessionP32745,P30936
    Uniprot Entry NameSSR3_HUMAN,SSR3_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000278195
    Target ClassificationGPCR

    The target: SSTR3, gene name: SSTR3, also named as SS-3-R, SS3-R, SS3R, SSR-28. This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.