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Anti-SSR3/ SSTR3/ SS-3-R monoclonal antibody
Anti-SSR3/ SSTR3/ SS-3-R antibody for FACS & in-vivo assay
Go to SSTR3/SSTR3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T13644-Ab-1/ GM-Tg-hg-T13644-Ab-2 | Anti-Human SSTR3 monoclonal antibody | Human |
| GM-Tg-rg-T13644-Ab-1/ GM-Tg-rg-T13644-Ab-2 | Anti-Rat SSTR3 monoclonal antibody | Rat |
| GM-Tg-mg-T13644-Ab-1/ GM-Tg-mg-T13644-Ab-2 | Anti-Mouse SSTR3 monoclonal antibody | Mouse |
| GM-Tg-cynog-T13644-Ab-1/ GM-Tg-cynog-T13644-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SSTR3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T13644-Ab-1/ GM-Tg-felg-T13644-Ab-2 | Anti-Feline SSTR3 monoclonal antibody | Feline |
| GM-Tg-cang-T13644-Ab-1/ GM-Tg-cang-T13644-Ab-2 | Anti-Canine SSTR3 monoclonal antibody | Canine |
| GM-Tg-bovg-T13644-Ab-1/ GM-Tg-bovg-T13644-Ab-2 | Anti-Bovine SSTR3 monoclonal antibody | Bovine |
| GM-Tg-equg-T13644-Ab-1/ GM-Tg-equg-T13644-Ab-2 | Anti-Equine SSTR3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T13644-Ab-1/ GM-Tg-hg-T13644-Ab-2; GM-Tg-rg-T13644-Ab-1/ GM-Tg-rg-T13644-Ab-2; GM-Tg-mg-T13644-Ab-1/ GM-Tg-mg-T13644-Ab-2; GM-Tg-cynog-T13644-Ab-1/ GM-Tg-cynog-T13644-Ab-2; GM-Tg-felg-T13644-Ab-1/ GM-Tg-felg-T13644-Ab-2; GM-Tg-cang-T13644-Ab-1/ GM-Tg-cang-T13644-Ab-2; GM-Tg-bovg-T13644-Ab-1/ GM-Tg-bovg-T13644-Ab-2; GM-Tg-equg-T13644-Ab-1/ GM-Tg-equg-T13644-Ab-2 |
| Products Name | Anti-SSTR3 monoclonal antibody |
| Format | mab |
| Target Name | SSTR3 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SSTR3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SSR3/ SSTR3/ SS-3-R VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003671 | human SSTR3 Lentivirus particle |
| ORF Viral Vector | pGMLP003671 | human SSTR3 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004364 | mouse Sstr3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004364 | mouse Sstr3 Lentivirus particle |
Target information
| Target ID | GM-T13644 |
| Target Name | SSTR3 |
| Gene ID | 6753,20607,171044,696585,481272,101096494,518585,100069706 |
| Gene Symbol and Synonyms | Smstr-3,Smstr28,Smstr3,SS-3-R,SS3-R,SS3R,SSR-28,SST3,SSTR,SSTR3 |
| Uniprot Accession | P32745,P30936 |
| Uniprot Entry Name | SSR3_HUMAN,SSR3_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000278195 |
| Target Classification | GPCR |
The target: SSTR3, gene name: SSTR3, also named as SS-3-R, SS3-R, SS3R, SSR-28. This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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