Anti-MMUT monoclonal antibody

Pre-made anti-MMUT monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MMUT/MMUT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T15569-Ab-1/ GM-Tg-hg-T15569-Ab-2Anti-Human MMUT monoclonal antibodyHuman
GM-Tg-rg-T15569-Ab-1/ GM-Tg-rg-T15569-Ab-2Anti-Rat MMUT monoclonal antibodyRat
GM-Tg-mg-T15569-Ab-1/ GM-Tg-mg-T15569-Ab-2Anti-Mouse MMUT monoclonal antibodyMouse
GM-Tg-cynog-T15569-Ab-1/ GM-Tg-cynog-T15569-Ab-2Anti-Cynomolgus/ Rhesus macaque MMUT monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T15569-Ab-1/ GM-Tg-felg-T15569-Ab-2Anti-Feline MMUT monoclonal antibodyFeline
GM-Tg-cang-T15569-Ab-1/ GM-Tg-cang-T15569-Ab-2Anti-Canine MMUT monoclonal antibodyCanine
GM-Tg-bovg-T15569-Ab-1/ GM-Tg-bovg-T15569-Ab-2Anti-Bovine MMUT monoclonal antibodyBovine
GM-Tg-equg-T15569-Ab-1/ GM-Tg-equg-T15569-Ab-2Anti-Equine MMUT monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T15569-Ab-1/ GM-Tg-hg-T15569-Ab-2; GM-Tg-rg-T15569-Ab-1/ GM-Tg-rg-T15569-Ab-2;
GM-Tg-mg-T15569-Ab-1/ GM-Tg-mg-T15569-Ab-2; GM-Tg-cynog-T15569-Ab-1/ GM-Tg-cynog-T15569-Ab-2;
GM-Tg-felg-T15569-Ab-1/ GM-Tg-felg-T15569-Ab-2; GM-Tg-cang-T15569-Ab-1/ GM-Tg-cang-T15569-Ab-2;
GM-Tg-bovg-T15569-Ab-1/ GM-Tg-bovg-T15569-Ab-2; GM-Tg-equg-T15569-Ab-1/ GM-Tg-equg-T15569-Ab-2
Products NameAnti-MMUT monoclonal antibody
Formatmab
Target NameMMUT
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MMUT monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T15569-Ag-1Recombinant multi-species MUTA/ MMUT/ MCM protein


    Target information

    Target IDGM-T15569
    Target NameMMUT
    Gene ID4594,17850,688517,706189,474930,101081046,280871,100055925
    Gene Symbol and SynonymsD230010K02Rik,MCM,MMUT,MUT
    Uniprot AccessionP22033,Q9GK13
    Uniprot Entry NameMUTA_HUMAN,MUTA_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000146085
    Target ClassificationN/A

    The target: MMUT, gene name: MMUT, also named as MCM, MUT. This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.