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Anti-HPGDS monoclonal antibody
Pre-made anti-HPGDS monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to HPGDS/HPGDS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T19433-Ab-1/ GM-Tg-hg-T19433-Ab-2 | Anti-Human HPGDS monoclonal antibody | Human |
| GM-Tg-rg-T19433-Ab-1/ GM-Tg-rg-T19433-Ab-2 | Anti-Rat HPGDS monoclonal antibody | Rat |
| GM-Tg-mg-T19433-Ab-1/ GM-Tg-mg-T19433-Ab-2 | Anti-Mouse HPGDS monoclonal antibody | Mouse |
| GM-Tg-cynog-T19433-Ab-1/ GM-Tg-cynog-T19433-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HPGDS monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T19433-Ab-1/ GM-Tg-felg-T19433-Ab-2 | Anti-Feline HPGDS monoclonal antibody | Feline |
| GM-Tg-cang-T19433-Ab-1/ GM-Tg-cang-T19433-Ab-2 | Anti-Canine HPGDS monoclonal antibody | Canine |
| GM-Tg-bovg-T19433-Ab-1/ GM-Tg-bovg-T19433-Ab-2 | Anti-Bovine HPGDS monoclonal antibody | Bovine |
| GM-Tg-equg-T19433-Ab-1/ GM-Tg-equg-T19433-Ab-2 | Anti-Equine HPGDS monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T19433-Ab-1/ GM-Tg-hg-T19433-Ab-2; GM-Tg-rg-T19433-Ab-1/ GM-Tg-rg-T19433-Ab-2; GM-Tg-mg-T19433-Ab-1/ GM-Tg-mg-T19433-Ab-2; GM-Tg-cynog-T19433-Ab-1/ GM-Tg-cynog-T19433-Ab-2; GM-Tg-felg-T19433-Ab-1/ GM-Tg-felg-T19433-Ab-2; GM-Tg-cang-T19433-Ab-1/ GM-Tg-cang-T19433-Ab-2; GM-Tg-bovg-T19433-Ab-1/ GM-Tg-bovg-T19433-Ab-2; GM-Tg-equg-T19433-Ab-1/ GM-Tg-equg-T19433-Ab-2 |
| Products Name | Anti-HPGDS monoclonal antibody |
| Format | mab |
| Target Name | HPGDS |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-HPGDS monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T19433-Ag-1 | Recombinant multi-species HPGDS/ GSTS/ GSTS1 protein |
Target information
| Target ID | GM-T19433 |
| Target Name | HPGDS |
| Gene ID | 27306,54486,58962,705227,478481,101083337,100139892,100053460 |
| Gene Symbol and Synonyms | GSTS,GSTS1,GSTS1-1,H-PGDS,HPGDS,PGD2,PGDS,Ptgds2 |
| Uniprot Accession | O60760,O35543 |
| Uniprot Entry Name | HPGDS_HUMAN,HPGDS_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000163106 |
| Target Classification | N/A |
The target: HPGDS, gene name: HPGDS, also named as GSTS, GSTS1, GSTS1-1, PGD2, PGDS. Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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