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Anti-CSF3/ C17orf33OS/ GCSF functional antibody
Anti-CSF3/ C17orf33OS/ GCSF functional antibody for cell culture, ELISA & in-vivo assay
Go to CSF3/CSF3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T19615-Ab-1/ GM-Tg-hg-T19615-Ab-2 | Anti-Human CSF3 monoclonal antibody | Human |
| GM-Tg-rg-T19615-Ab-1/ GM-Tg-rg-T19615-Ab-2 | Anti-Rat CSF3 monoclonal antibody | Rat |
| GM-Tg-mg-T19615-Ab-1/ GM-Tg-mg-T19615-Ab-2 | Anti-Mouse CSF3 monoclonal antibody | Mouse |
| GM-Tg-cynog-T19615-Ab-1/ GM-Tg-cynog-T19615-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CSF3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T19615-Ab-1/ GM-Tg-felg-T19615-Ab-2 | Anti-Feline CSF3 monoclonal antibody | Feline |
| GM-Tg-cang-T19615-Ab-1/ GM-Tg-cang-T19615-Ab-2 | Anti-Canine CSF3 monoclonal antibody | Canine |
| GM-Tg-bovg-T19615-Ab-1/ GM-Tg-bovg-T19615-Ab-2 | Anti-Bovine CSF3 monoclonal antibody | Bovine |
| GM-Tg-equg-T19615-Ab-1/ GM-Tg-equg-T19615-Ab-2 | Anti-Equine CSF3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T19615-Ab-1/ GM-Tg-hg-T19615-Ab-2; GM-Tg-rg-T19615-Ab-1/ GM-Tg-rg-T19615-Ab-2; GM-Tg-mg-T19615-Ab-1/ GM-Tg-mg-T19615-Ab-2; GM-Tg-cynog-T19615-Ab-1/ GM-Tg-cynog-T19615-Ab-2; GM-Tg-felg-T19615-Ab-1/ GM-Tg-felg-T19615-Ab-2; GM-Tg-cang-T19615-Ab-1/ GM-Tg-cang-T19615-Ab-2; GM-Tg-bovg-T19615-Ab-1/ GM-Tg-bovg-T19615-Ab-2; GM-Tg-equg-T19615-Ab-1/ GM-Tg-equg-T19615-Ab-2 |
| Products Name | Anti-CSF3 monoclonal antibody |
| Format | mab |
| Target Name | CSF3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CSF3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T19615-Ag-1 | Recombinant multi-species CSF3/ C17orf33OS/ GCSF protein |
| ORF Viral Vector | vGMLP004541 | human CSF3 Lentivirus particle |
| ORF Viral Vector | pGMLP004541 | human CSF3 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004333 | mouse Csf3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004333 | mouse Csf3 Lentivirus particle |
Target information
| Target ID | GM-T19615 |
| Target Name | CSF3 |
| Gene ID | 1440,12985,25610,698961,608246,493700,281096,100033922 |
| Gene Symbol and Synonyms | C17orf33,CSF3,CSF3OS,Csfg,G-CSF,GCSF,MGI-IG |
| Uniprot Accession | P09919,P35834,O02708,P35833 |
| Uniprot Entry Name | CSF3_HUMAN,CSF3_FELCA,CSF3_CANLF,CSF3_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target |
| Disease | metastatic tumors |
| Gene Ensembl | ENSG00000108342 |
| Target Classification | N/A |
The target: CSF3, gene name: CSF3, also named as C17orf33OS, GCSF, CSF3. This gene encodes a member of the IL-6 superfamily of cytokines. The encoded cytokine controls the production, differentiation, and function of granulocytes. Granulocytes are a type of white blood cell that are part of the innate immune response. A modified form of this protein is commonly administered to manage chemotherapy-induced neutropenia. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2020].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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