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Anti-CELA1/ ELA1 functional antibody
Anti-CELA1/ ELA1 functional antibody for cell culture, ELISA & in-vivo assay
Go to CELA1/CELA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T22839-Ab-1/ GM-Tg-hg-T22839-Ab-2 | Anti-Human CELA1 monoclonal antibody | Human |
| GM-Tg-rg-T22839-Ab-1/ GM-Tg-rg-T22839-Ab-2 | Anti-Rat CELA1 monoclonal antibody | Rat |
| GM-Tg-mg-T22839-Ab-1/ GM-Tg-mg-T22839-Ab-2 | Anti-Mouse CELA1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T22839-Ab-1/ GM-Tg-cynog-T22839-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CELA1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T22839-Ab-1/ GM-Tg-felg-T22839-Ab-2 | Anti-Feline CELA1 monoclonal antibody | Feline |
| GM-Tg-cang-T22839-Ab-1/ GM-Tg-cang-T22839-Ab-2 | Anti-Canine CELA1 monoclonal antibody | Canine |
| GM-Tg-bovg-T22839-Ab-1/ GM-Tg-bovg-T22839-Ab-2 | Anti-Bovine CELA1 monoclonal antibody | Bovine |
| GM-Tg-equg-T22839-Ab-1/ GM-Tg-equg-T22839-Ab-2 | Anti-Equine CELA1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T22839-Ab-1/ GM-Tg-hg-T22839-Ab-2; GM-Tg-rg-T22839-Ab-1/ GM-Tg-rg-T22839-Ab-2; GM-Tg-mg-T22839-Ab-1/ GM-Tg-mg-T22839-Ab-2; GM-Tg-cynog-T22839-Ab-1/ GM-Tg-cynog-T22839-Ab-2; GM-Tg-felg-T22839-Ab-1/ GM-Tg-felg-T22839-Ab-2; GM-Tg-cang-T22839-Ab-1/ GM-Tg-cang-T22839-Ab-2; GM-Tg-bovg-T22839-Ab-1/ GM-Tg-bovg-T22839-Ab-2; GM-Tg-equg-T22839-Ab-1/ GM-Tg-equg-T22839-Ab-2 |
| Products Name | Anti-CELA1 monoclonal antibody |
| Format | mab |
| Target Name | CELA1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CELA1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T22839-Ag-1 | Recombinant multi-species CELA1/ ELA1 protein |
Target information
| Target ID | GM-T22839 |
| Target Name | CELA1 |
| Gene ID | 1990,109901,24331,695507,494217,281139,100052672 |
| Gene Symbol and Synonyms | 1810009A17Rik,1810062B19Rik,CELA1,Ela-1,ELA1,ELAI1,ELS1,PC-TsF,RATELAI1 |
| Uniprot Accession | Q9UNI1,P00773,Q5R1M5,Q28153 |
| Uniprot Entry Name | CELA1_HUMAN,CELA1_RAT,CELA1_FELCA,CELA1_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000139610 |
| Target Classification | N/A |
The target: CELA1, gene name: CELA1, also named as ELA1. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B. [provided by RefSeq, May 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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