- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-PPP3CA monoclonal antibody
Pre-made anti-PPP3CA monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PPP3CA/PPP3CA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T25464-Ab-1/ GM-Tg-hg-T25464-Ab-2 | Anti-Human PPP3CA monoclonal antibody | Human |
| GM-Tg-rg-T25464-Ab-1/ GM-Tg-rg-T25464-Ab-2 | Anti-Rat PPP3CA monoclonal antibody | Rat |
| GM-Tg-mg-T25464-Ab-1/ GM-Tg-mg-T25464-Ab-2 | Anti-Mouse PPP3CA monoclonal antibody | Mouse |
| GM-Tg-cynog-T25464-Ab-1/ GM-Tg-cynog-T25464-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PPP3CA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T25464-Ab-1/ GM-Tg-felg-T25464-Ab-2 | Anti-Feline PPP3CA monoclonal antibody | Feline |
| GM-Tg-cang-T25464-Ab-1/ GM-Tg-cang-T25464-Ab-2 | Anti-Canine PPP3CA monoclonal antibody | Canine |
| GM-Tg-bovg-T25464-Ab-1/ GM-Tg-bovg-T25464-Ab-2 | Anti-Bovine PPP3CA monoclonal antibody | Bovine |
| GM-Tg-equg-T25464-Ab-1/ GM-Tg-equg-T25464-Ab-2 | Anti-Equine PPP3CA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T25464-Ab-1/ GM-Tg-hg-T25464-Ab-2; GM-Tg-rg-T25464-Ab-1/ GM-Tg-rg-T25464-Ab-2; GM-Tg-mg-T25464-Ab-1/ GM-Tg-mg-T25464-Ab-2; GM-Tg-cynog-T25464-Ab-1/ GM-Tg-cynog-T25464-Ab-2; GM-Tg-felg-T25464-Ab-1/ GM-Tg-felg-T25464-Ab-2; GM-Tg-cang-T25464-Ab-1/ GM-Tg-cang-T25464-Ab-2; GM-Tg-bovg-T25464-Ab-1/ GM-Tg-bovg-T25464-Ab-2; GM-Tg-equg-T25464-Ab-1/ GM-Tg-equg-T25464-Ab-2 |
| Products Name | Anti-PPP3CA monoclonal antibody |
| Format | mab |
| Target Name | PPP3CA |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PPP3CA monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T25464-Ag-1 | Recombinant multi-species PP2BA/ PPP3CA/ CALN protein |
Target information
| Target ID | GM-T25464 |
| Target Name | PPP3CA |
| Gene ID | 5530,19055,24674,709773,403486,101097144,286852,100067434 |
| Gene Symbol and Synonyms | 2900074D19Rik,ACCIID,CALN,CALNA,CALNA1,CCN1,CN,CnA,CNA1,DEE91,IECEE,IECEE1,PPP2B,PPP3CA |
| Uniprot Accession | Q08209,P63329,P48452 |
| Uniprot Entry Name | PP2BA_HUMAN,PP2BA_RAT,PP2BA_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000138814 |
| Target Classification | N/A |
The target: PPP3CA, gene name: PPP3CA, also named as CALN, CALNA, CALNA1, CCN1, CNA1, IECEE, IECEE1, PPP2B. Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; peptidyl-serine dephosphorylation; and response to calcium ion. Located in several cellular components, including cytosol; dendritic spine; and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
