Anti-TRY1/ PRSS1/ TRP1 functional antibody
Anti-TRY1/ PRSS1/ TRP1 functional antibody for cell culture, ELISA & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T27602-Ab-1/ GM-Tg-hg-T27602-Ab-2 | Anti-Human PRSS1 monoclonal antibody | Human |
GM-Tg-rg-T27602-Ab-1/ GM-Tg-rg-T27602-Ab-2 | Anti-Rat PRSS1 monoclonal antibody | Rat |
GM-Tg-mg-T27602-Ab-1/ GM-Tg-mg-T27602-Ab-2 | Anti-Mouse PRSS1 monoclonal antibody | Mouse |
GM-Tg-cynog-T27602-Ab-1/ GM-Tg-cynog-T27602-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRSS1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T27602-Ab-1/ GM-Tg-felg-T27602-Ab-2 | Anti-Feline PRSS1 monoclonal antibody | Feline |
GM-Tg-cang-T27602-Ab-1/ GM-Tg-cang-T27602-Ab-2 | Anti-Canine PRSS1 monoclonal antibody | Canine |
GM-Tg-bovg-T27602-Ab-1/ GM-Tg-bovg-T27602-Ab-2 | Anti-Bovine PRSS1 monoclonal antibody | Bovine |
GM-Tg-equg-T27602-Ab-1/ GM-Tg-equg-T27602-Ab-2 | Anti-Equine PRSS1 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T27602-Ab-1/ GM-Tg-hg-T27602-Ab-2; GM-Tg-rg-T27602-Ab-1/ GM-Tg-rg-T27602-Ab-2; GM-Tg-mg-T27602-Ab-1/ GM-Tg-mg-T27602-Ab-2; GM-Tg-cynog-T27602-Ab-1/ GM-Tg-cynog-T27602-Ab-2; GM-Tg-felg-T27602-Ab-1/ GM-Tg-felg-T27602-Ab-2; GM-Tg-cang-T27602-Ab-1/ GM-Tg-cang-T27602-Ab-2; GM-Tg-bovg-T27602-Ab-1/ GM-Tg-bovg-T27602-Ab-2; GM-Tg-equg-T27602-Ab-1/ GM-Tg-equg-T27602-Ab-2 |
Products Name | Anti-PRSS1 monoclonal antibody |
Format | mab |
Target Name | PRSS1 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-PRSS1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-T27602-Ag-1 | Recombinant multi-species TRY1/ PRSS1/ TRP1 protein |
ORF Viral Vector | pGMLP000797 | human PRSS1 Lentivirus plasmid |
ORF Viral Vector | vGMLP000797 | human PRSS1 Lentivirus particle |
ORF Viral Vector | pGMLPm004527 | mouse Prss1 Lentivirus plasmid |
ORF Viral Vector | vGMLPm004527 | mouse Prss1 Lentivirus particle |
Target information
Target ID | GM-T27602 |
Target Name | PRSS1 |
Gene ID | 5644 |
Gene Symbol and Synonyms | PRSS1,TRP1,TRY1,TRY4,TRYP1 |
Uniprot Accession | P07477 |
Uniprot Entry Name | TRY1_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000204983 |
Target Classification | Tumor-associated antigen (TAA) |
The target: PRSS1, gene name: PRSS1, also named as TRP1, TRY1, TRY4, TRYP1. This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.