Anti-CCKAR/ CCK-A/ CCK1-R monoclonal antibody

Anti-CCKAR/ CCK-A/ CCK1-R antibody for FACS & in-vivo assay

Target products collectionGo to CCKAR/CCKAR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T28330-Ab-1/ GM-Tg-hg-T28330-Ab-2Anti-Human CCKAR monoclonal antibodyHuman
GM-Tg-rg-T28330-Ab-1/ GM-Tg-rg-T28330-Ab-2Anti-Rat CCKAR monoclonal antibodyRat
GM-Tg-mg-T28330-Ab-1/ GM-Tg-mg-T28330-Ab-2Anti-Mouse CCKAR monoclonal antibodyMouse
GM-Tg-cynog-T28330-Ab-1/ GM-Tg-cynog-T28330-Ab-2Anti-Cynomolgus/ Rhesus macaque CCKAR monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T28330-Ab-1/ GM-Tg-felg-T28330-Ab-2Anti-Feline CCKAR monoclonal antibodyFeline
GM-Tg-cang-T28330-Ab-1/ GM-Tg-cang-T28330-Ab-2Anti-Canine CCKAR monoclonal antibodyCanine
GM-Tg-bovg-T28330-Ab-1/ GM-Tg-bovg-T28330-Ab-2Anti-Bovine CCKAR monoclonal antibodyBovine
GM-Tg-equg-T28330-Ab-1/ GM-Tg-equg-T28330-Ab-2Anti-Equine CCKAR monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T28330-Ab-1/ GM-Tg-hg-T28330-Ab-2; GM-Tg-rg-T28330-Ab-1/ GM-Tg-rg-T28330-Ab-2;
GM-Tg-mg-T28330-Ab-1/ GM-Tg-mg-T28330-Ab-2; GM-Tg-cynog-T28330-Ab-1/ GM-Tg-cynog-T28330-Ab-2;
GM-Tg-felg-T28330-Ab-1/ GM-Tg-felg-T28330-Ab-2; GM-Tg-cang-T28330-Ab-1/ GM-Tg-cang-T28330-Ab-2;
GM-Tg-bovg-T28330-Ab-1/ GM-Tg-bovg-T28330-Ab-2; GM-Tg-equg-T28330-Ab-1/ GM-Tg-equg-T28330-Ab-2
Products NameAnti-CCKAR monoclonal antibody
Target NameCCKAR
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-CCKAR benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CCKAR/ CCK-A/ CCK1-R VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP002992human CCKAR Lentivirus particle
    ORF Viral VectorpGMLP002992human CCKAR Lentivirus plasmid
    ORF Viral VectorpGMLPm001768mouse Cckar Lentivirus plasmid
    ORF Viral VectorvGMLPm001768mouse Cckar Lentivirus particle

    Target information

    Target IDGM-T28330
    Target NameCCKAR
    Gene ID886,12425,24889,694742,488846,101099960,506207,100055506
    Gene Symbol and SynonymsCCK-A,Cck-ar,CCK1-R,CCK1R,CCKAR,CCKRA
    Uniprot AccessionP32238,P30551,Q5D0K2
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    Gene EnsemblENSG00000163394
    Target ClassificationGPCR

    The target: CCKAR, gene name: CCKAR, also named as CCK-A, CCK1-R, CCK1R, CCKRA. This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine. [provided by RefSeq, Jul 2008].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.