Anti-ADA1B/ ADRA1B/ ADRA1 monoclonal antibody

Anti-ADA1B/ ADRA1B/ ADRA1 antibody for FACS & in-vivo assay

Target products collectionGo to ADRA1B/ADRA1B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T29500-Ab-1/ GM-Tg-hg-T29500-Ab-2Anti-Human ADRA1B monoclonal antibodyHuman
GM-Tg-rg-T29500-Ab-1/ GM-Tg-rg-T29500-Ab-2Anti-Rat ADRA1B monoclonal antibodyRat
GM-Tg-mg-T29500-Ab-1/ GM-Tg-mg-T29500-Ab-2Anti-Mouse ADRA1B monoclonal antibodyMouse
GM-Tg-cynog-T29500-Ab-1/ GM-Tg-cynog-T29500-Ab-2Anti-Cynomolgus/ Rhesus macaque ADRA1B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T29500-Ab-1/ GM-Tg-felg-T29500-Ab-2Anti-Feline ADRA1B monoclonal antibodyFeline
GM-Tg-cang-T29500-Ab-1/ GM-Tg-cang-T29500-Ab-2Anti-Canine ADRA1B monoclonal antibodyCanine
GM-Tg-bovg-T29500-Ab-1/ GM-Tg-bovg-T29500-Ab-2Anti-Bovine ADRA1B monoclonal antibodyBovine
GM-Tg-equg-T29500-Ab-1/ GM-Tg-equg-T29500-Ab-2Anti-Equine ADRA1B monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T29500-Ab-1/ GM-Tg-hg-T29500-Ab-2; GM-Tg-rg-T29500-Ab-1/ GM-Tg-rg-T29500-Ab-2;
GM-Tg-mg-T29500-Ab-1/ GM-Tg-mg-T29500-Ab-2; GM-Tg-cynog-T29500-Ab-1/ GM-Tg-cynog-T29500-Ab-2;
GM-Tg-felg-T29500-Ab-1/ GM-Tg-felg-T29500-Ab-2; GM-Tg-cang-T29500-Ab-1/ GM-Tg-cang-T29500-Ab-2;
GM-Tg-bovg-T29500-Ab-1/ GM-Tg-bovg-T29500-Ab-2; GM-Tg-equg-T29500-Ab-1/ GM-Tg-equg-T29500-Ab-2
Products NameAnti-ADRA1B monoclonal antibody
Target NameADRA1B
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-ADRA1B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ADA1B/ ADRA1B/ ADRA1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm005344mouse Adra1b Lentivirus plasmid
    ORF Viral VectorvGMLPm005344mouse Adra1b Lentivirus particle

    Target information

    Target IDGM-T29500
    Target NameADRA1B
    Gene ID147,11548,24173,695106,403962,101092238,407140,100071055
    Gene Symbol and SynonymsADRA1,ADRA1B,ALPHA1BAR,RDC5,[a]1b
    Uniprot AccessionP35368,P15823,P11615
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    Gene EnsemblENSG00000170214
    Target ClassificationGPCR

    The target: ADRA1B, gene name: ADRA1B, also named as ADRA1, ALPHA1BAR. Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.