Anti-PLF4/ PF4/ CXCL4 functional antibody

Anti-PLF4/ PF4/ CXCL4 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to PF4/PF4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T30827-Ab-1/ GM-Tg-hg-T30827-Ab-2Anti-Human PF4 monoclonal antibodyHuman
GM-Tg-rg-T30827-Ab-1/ GM-Tg-rg-T30827-Ab-2Anti-Rat PF4 monoclonal antibodyRat
GM-Tg-mg-T30827-Ab-1/ GM-Tg-mg-T30827-Ab-2Anti-Mouse PF4 monoclonal antibodyMouse
GM-Tg-cynog-T30827-Ab-1/ GM-Tg-cynog-T30827-Ab-2Anti-Cynomolgus/ Rhesus macaque PF4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T30827-Ab-1/ GM-Tg-felg-T30827-Ab-2Anti-Feline PF4 monoclonal antibodyFeline
GM-Tg-cang-T30827-Ab-1/ GM-Tg-cang-T30827-Ab-2Anti-Canine PF4 monoclonal antibodyCanine
GM-Tg-bovg-T30827-Ab-1/ GM-Tg-bovg-T30827-Ab-2Anti-Bovine PF4 monoclonal antibodyBovine
GM-Tg-equg-T30827-Ab-1/ GM-Tg-equg-T30827-Ab-2Anti-Equine PF4 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T30827-Ab-1/ GM-Tg-hg-T30827-Ab-2; GM-Tg-rg-T30827-Ab-1/ GM-Tg-rg-T30827-Ab-2;
GM-Tg-mg-T30827-Ab-1/ GM-Tg-mg-T30827-Ab-2; GM-Tg-cynog-T30827-Ab-1/ GM-Tg-cynog-T30827-Ab-2;
GM-Tg-felg-T30827-Ab-1/ GM-Tg-felg-T30827-Ab-2; GM-Tg-cang-T30827-Ab-1/ GM-Tg-cang-T30827-Ab-2;
GM-Tg-bovg-T30827-Ab-1/ GM-Tg-bovg-T30827-Ab-2; GM-Tg-equg-T30827-Ab-1/ GM-Tg-equg-T30827-Ab-2
Products NameAnti-PF4 monoclonal antibody
Target NamePF4
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-PF4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T30827-Ag-1Recombinant multi-species PLF4/ PF4/ CXCL4 protein
    CytokineGM-Tg-g-T30827-Ag-1platelet factor 4 (PF4) protein
    ORF Viral VectorvGMLP004508human PF4 Lentivirus particle
    ORF Viral VectorpGMLP004508human PF4 Lentivirus plasmid
    ORF Viral VectorpGMLPm000559mouse Pf4 Lentivirus plasmid
    ORF Viral VectorvGMLPm000559mouse Pf4 Lentivirus particle

    Target information

    Target IDGM-T30827
    Target NamePF4
    Gene ID5196,56744,360918,703451,507790,100630489
    Gene Symbol and SynonymsCXCL4,LOC100630489,PF-4,PF4,Pf4a,RATPF4A,SCYB4
    Uniprot AccessionP02776,P06765,P02777
    Uniprot Entry NamePLF4_HUMAN,PLF4_RAT,PLF4_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryTherapeutics Target, Cytokine Target
    Gene EnsemblENSG00000163737
    Target ClassificationN/A

    The target: PF4, gene name: PF4, also named as CXCL4, PF-4, SCYB4. This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.