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Anti-CAMP/ CAP-18/ CAP18 functional antibody
Anti-CAMP/ CAP-18/ CAP18 functional antibody for cell culture, ELISA & in-vivo assay
Go to CAMP/CAMP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T34318-Ab-1/ GM-Tg-hg-T34318-Ab-2 | Anti-Human CAMP monoclonal antibody | Human |
| GM-Tg-rg-T34318-Ab-1/ GM-Tg-rg-T34318-Ab-2 | Anti-Rat CAMP monoclonal antibody | Rat |
| GM-Tg-mg-T34318-Ab-1/ GM-Tg-mg-T34318-Ab-2 | Anti-Mouse CAMP monoclonal antibody | Mouse |
| GM-Tg-cynog-T34318-Ab-1/ GM-Tg-cynog-T34318-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CAMP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T34318-Ab-1/ GM-Tg-felg-T34318-Ab-2 | Anti-Feline CAMP monoclonal antibody | Feline |
| GM-Tg-cang-T34318-Ab-1/ GM-Tg-cang-T34318-Ab-2 | Anti-Canine CAMP monoclonal antibody | Canine |
| GM-Tg-bovg-T34318-Ab-1/ GM-Tg-bovg-T34318-Ab-2 | Anti-Bovine CAMP monoclonal antibody | Bovine |
| GM-Tg-equg-T34318-Ab-1/ GM-Tg-equg-T34318-Ab-2 | Anti-Equine CAMP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T34318-Ab-1/ GM-Tg-hg-T34318-Ab-2; GM-Tg-rg-T34318-Ab-1/ GM-Tg-rg-T34318-Ab-2; GM-Tg-mg-T34318-Ab-1/ GM-Tg-mg-T34318-Ab-2; GM-Tg-cynog-T34318-Ab-1/ GM-Tg-cynog-T34318-Ab-2; GM-Tg-felg-T34318-Ab-1/ GM-Tg-felg-T34318-Ab-2; GM-Tg-cang-T34318-Ab-1/ GM-Tg-cang-T34318-Ab-2; GM-Tg-bovg-T34318-Ab-1/ GM-Tg-bovg-T34318-Ab-2; GM-Tg-equg-T34318-Ab-1/ GM-Tg-equg-T34318-Ab-2 |
| Products Name | Anti-CAMP monoclonal antibody |
| Format | mab |
| Target Name | CAMP |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CAMP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T34318-Ag-1 | Recombinant multi-species CAMP/ CAP-18/ CAP18 protein |
| ORF Viral Vector | vGMLP000854 | human CAMP Lentivirus particle |
| ORF Viral Vector | pGMLP000854 | human CAMP Lentivirus plasmid |
| ORF Viral Vector | pGMAD000229 | mouse Camp Adenovirus plasmid |
| ORF Viral Vector | pGMAD000456 | house mouse Camp Adenovirus plasmid |
| ORF Viral Vector | pGMLPm000037 | mouse Camp Lentivirus plasmid |
| ORF Viral Vector | vGMAD000229 | mouse Camp Adenovirus particle |
| ORF Viral Vector | vGMAD000456 | house mouse Camp Adenovirus particle |
| ORF Viral Vector | vGMLPm000037 | mouse Camp Lentivirus particle |
Target information
| Target ID | GM-T34318 |
| Target Name | CAMP |
| Gene ID | 820,12796,316010,619186,442947,100533978 |
| Gene Symbol and Synonyms | CAMP,CAP-18,CAP18,CLP,Cnlp,CRAMP,FALL-39,FALL39,HSD26,LL37,MCLP |
| Uniprot Accession | P49913,Q9GLV5 |
| Uniprot Entry Name | CAMP_HUMAN,CAMP_MACMU |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000164047 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: CAMP, gene name: CAMP, also named as CAP-18, CAP18, CRAMP, FALL-39, FALL39, HSD26, LL37. This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. The protein plays an important role in innate immunity defense against viruses. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2021].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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