Anti-GLP2R monoclonal antibody
Anti-GLP2R antibody for FACS & in-vivo assay
Go to GLP2R/GLP2R products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T34843-Ab-1/ GM-Tg-hg-T34843-Ab-2 | Anti-Human GLP2R monoclonal antibody | Human |
GM-Tg-rg-T34843-Ab-1/ GM-Tg-rg-T34843-Ab-2 | Anti-Rat GLP2R monoclonal antibody | Rat |
GM-Tg-mg-T34843-Ab-1/ GM-Tg-mg-T34843-Ab-2 | Anti-Mouse GLP2R monoclonal antibody | Mouse |
GM-Tg-cynog-T34843-Ab-1/ GM-Tg-cynog-T34843-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GLP2R monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T34843-Ab-1/ GM-Tg-felg-T34843-Ab-2 | Anti-Feline GLP2R monoclonal antibody | Feline |
GM-Tg-cang-T34843-Ab-1/ GM-Tg-cang-T34843-Ab-2 | Anti-Canine GLP2R monoclonal antibody | Canine |
GM-Tg-bovg-T34843-Ab-1/ GM-Tg-bovg-T34843-Ab-2 | Anti-Bovine GLP2R monoclonal antibody | Bovine |
GM-Tg-equg-T34843-Ab-1/ GM-Tg-equg-T34843-Ab-2 | Anti-Equine GLP2R monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T34843-Ab-1/ GM-Tg-hg-T34843-Ab-2; GM-Tg-rg-T34843-Ab-1/ GM-Tg-rg-T34843-Ab-2; GM-Tg-mg-T34843-Ab-1/ GM-Tg-mg-T34843-Ab-2; GM-Tg-cynog-T34843-Ab-1/ GM-Tg-cynog-T34843-Ab-2; GM-Tg-felg-T34843-Ab-1/ GM-Tg-felg-T34843-Ab-2; GM-Tg-cang-T34843-Ab-1/ GM-Tg-cang-T34843-Ab-2; GM-Tg-bovg-T34843-Ab-1/ GM-Tg-bovg-T34843-Ab-2; GM-Tg-equg-T34843-Ab-1/ GM-Tg-equg-T34843-Ab-2 |
Products Name | Anti-GLP2R monoclonal antibody |
Format | mab |
Target Name | GLP2R |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-GLP2R benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Biosimilar | GMP-Bios-INN-1014 | |
Target Antigen | Products Developing | Multi-species GLP2R VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | pGMLP000792 | human GLP2R Lentivirus plasmid |
ORF Viral Vector | vGMLP000792 | human GLP2R Lentivirus particle |
ORF Viral Vector | pGMLPm005358 | mouse Glp2r Lentivirus plasmid |
ORF Viral Vector | pGMLPm005359 | mouse Glp2r Lentivirus plasmid |
ORF Viral Vector | vGMLPm005358 | mouse Glp2r Lentivirus particle |
ORF Viral Vector | vGMLPm005359 | mouse Glp2r Lentivirus particle |
Target information
Target ID | GM-T34843 |
Target Name | GLP2R |
Gene ID | 9340,93896,60432,717783,489499,101083631,511942,100073078 |
Gene Symbol and Synonyms | 9530092J08Rik,GLP-2,GLP2R |
Uniprot Accession | O95838,Q9Z0W0 |
Uniprot Entry Name | GLP2R_HUMAN,GLP2R_RAT |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, INN Index |
Disease | N/A |
Gene Ensembl | ENSG00000065325 |
Target Classification | N/A |
The target: GLP2R, gene name: GLP2R, also named as . This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.