Anti-GLP2R monoclonal antibody

Anti-GLP2R antibody for FACS & in-vivo assay

Target products collectionGo to GLP2R/GLP2R products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T34843-Ab-1/ GM-Tg-hg-T34843-Ab-2Anti-Human GLP2R monoclonal antibodyHuman
GM-Tg-rg-T34843-Ab-1/ GM-Tg-rg-T34843-Ab-2Anti-Rat GLP2R monoclonal antibodyRat
GM-Tg-mg-T34843-Ab-1/ GM-Tg-mg-T34843-Ab-2Anti-Mouse GLP2R monoclonal antibodyMouse
GM-Tg-cynog-T34843-Ab-1/ GM-Tg-cynog-T34843-Ab-2Anti-Cynomolgus/ Rhesus macaque GLP2R monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T34843-Ab-1/ GM-Tg-felg-T34843-Ab-2Anti-Feline GLP2R monoclonal antibodyFeline
GM-Tg-cang-T34843-Ab-1/ GM-Tg-cang-T34843-Ab-2Anti-Canine GLP2R monoclonal antibodyCanine
GM-Tg-bovg-T34843-Ab-1/ GM-Tg-bovg-T34843-Ab-2Anti-Bovine GLP2R monoclonal antibodyBovine
GM-Tg-equg-T34843-Ab-1/ GM-Tg-equg-T34843-Ab-2Anti-Equine GLP2R monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T34843-Ab-1/ GM-Tg-hg-T34843-Ab-2; GM-Tg-rg-T34843-Ab-1/ GM-Tg-rg-T34843-Ab-2;
GM-Tg-mg-T34843-Ab-1/ GM-Tg-mg-T34843-Ab-2; GM-Tg-cynog-T34843-Ab-1/ GM-Tg-cynog-T34843-Ab-2;
GM-Tg-felg-T34843-Ab-1/ GM-Tg-felg-T34843-Ab-2; GM-Tg-cang-T34843-Ab-1/ GM-Tg-cang-T34843-Ab-2;
GM-Tg-bovg-T34843-Ab-1/ GM-Tg-bovg-T34843-Ab-2; GM-Tg-equg-T34843-Ab-1/ GM-Tg-equg-T34843-Ab-2
Products NameAnti-GLP2R monoclonal antibody
Formatmab
Target NameGLP2R
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GLP2R benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    BiosimilarGMP-Bios-INN-1014
    Target AntigenProducts DevelopingMulti-species GLP2R VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP000792human GLP2R Lentivirus plasmid
    ORF Viral VectorvGMLP000792human GLP2R Lentivirus particle
    ORF Viral VectorpGMLPm005358mouse Glp2r Lentivirus plasmid
    ORF Viral VectorpGMLPm005359mouse Glp2r Lentivirus plasmid
    ORF Viral VectorvGMLPm005358mouse Glp2r Lentivirus particle
    ORF Viral VectorvGMLPm005359mouse Glp2r Lentivirus particle


    Target information

    Target IDGM-T34843
    Target NameGLP2R
    Gene ID9340,93896,60432,717783,489499,101083631,511942,100073078
    Gene Symbol and Synonyms9530092J08Rik,GLP-2,GLP2R
    Uniprot AccessionO95838,Q9Z0W0
    Uniprot Entry NameGLP2R_HUMAN,GLP2R_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, INN Index
    DiseaseN/A
    Gene EnsemblENSG00000065325
    Target ClassificationN/A

    The target: GLP2R, gene name: GLP2R, also named as . This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.