Anti-AA3R/ ADORA3/ A3AR monoclonal antibody

Anti-AA3R/ ADORA3/ A3AR antibody for FACS & in-vivo assay

Target products collectionGo to ADORA3/ADORA3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T36059-Ab-1/ GM-Tg-hg-T36059-Ab-2Anti-Human ADORA3 monoclonal antibodyHuman
GM-Tg-rg-T36059-Ab-1/ GM-Tg-rg-T36059-Ab-2Anti-Rat ADORA3 monoclonal antibodyRat
GM-Tg-mg-T36059-Ab-1/ GM-Tg-mg-T36059-Ab-2Anti-Mouse ADORA3 monoclonal antibodyMouse
GM-Tg-cynog-T36059-Ab-1/ GM-Tg-cynog-T36059-Ab-2Anti-Cynomolgus/ Rhesus macaque ADORA3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T36059-Ab-1/ GM-Tg-felg-T36059-Ab-2Anti-Feline ADORA3 monoclonal antibodyFeline
GM-Tg-cang-T36059-Ab-1/ GM-Tg-cang-T36059-Ab-2Anti-Canine ADORA3 monoclonal antibodyCanine
GM-Tg-bovg-T36059-Ab-1/ GM-Tg-bovg-T36059-Ab-2Anti-Bovine ADORA3 monoclonal antibodyBovine
GM-Tg-equg-T36059-Ab-1/ GM-Tg-equg-T36059-Ab-2Anti-Equine ADORA3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T36059-Ab-1/ GM-Tg-hg-T36059-Ab-2; GM-Tg-rg-T36059-Ab-1/ GM-Tg-rg-T36059-Ab-2;
GM-Tg-mg-T36059-Ab-1/ GM-Tg-mg-T36059-Ab-2; GM-Tg-cynog-T36059-Ab-1/ GM-Tg-cynog-T36059-Ab-2;
GM-Tg-felg-T36059-Ab-1/ GM-Tg-felg-T36059-Ab-2; GM-Tg-cang-T36059-Ab-1/ GM-Tg-cang-T36059-Ab-2;
GM-Tg-bovg-T36059-Ab-1/ GM-Tg-bovg-T36059-Ab-2; GM-Tg-equg-T36059-Ab-1/ GM-Tg-equg-T36059-Ab-2
Products NameAnti-ADORA3 monoclonal antibody
Target NameADORA3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-ADORA3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species AA3R/ ADORA3/ A3AR VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP003536human ADORA3 Lentivirus particle
    ORF Viral VectorpGMLP003536human ADORA3 Lentivirus plasmid
    ORF Viral VectorpGMLPm000883mouse Adora3 Lentivirus plasmid
    ORF Viral VectorvGMLPm000883mouse Adora3 Lentivirus particle

    Target information

    Target IDGM-T36059
    Target NameADORA3
    Gene ID140,100911796,403805,101094689
    Gene Symbol and SynonymsA3,A3AR,ADORA3,TGPCR1
    Uniprot AccessionP0DMS8,Q28309
    Uniprot Entry NameAA3R_HUMAN,AA3R_CANLF
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, Immuno-oncology Target
    Gene EnsemblENSG00000282608
    Target ClassificationCheckpoint-Immuno Oncology, GPCR

    The target: ADORA3, gene name: ADORA3, also named as A3AR. This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.