Anti-BLVRA monoclonal antibody

Pre-made anti-BLVRA monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to BLVRA/BLVRA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T37046-Ab-1/ GM-Tg-hg-T37046-Ab-2Anti-Human BLVRA monoclonal antibodyHuman
GM-Tg-rg-T37046-Ab-1/ GM-Tg-rg-T37046-Ab-2Anti-Rat BLVRA monoclonal antibodyRat
GM-Tg-mg-T37046-Ab-1/ GM-Tg-mg-T37046-Ab-2Anti-Mouse BLVRA monoclonal antibodyMouse
GM-Tg-cynog-T37046-Ab-1/ GM-Tg-cynog-T37046-Ab-2Anti-Cynomolgus/ Rhesus macaque BLVRA monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T37046-Ab-1/ GM-Tg-felg-T37046-Ab-2Anti-Feline BLVRA monoclonal antibodyFeline
GM-Tg-cang-T37046-Ab-1/ GM-Tg-cang-T37046-Ab-2Anti-Canine BLVRA monoclonal antibodyCanine
GM-Tg-bovg-T37046-Ab-1/ GM-Tg-bovg-T37046-Ab-2Anti-Bovine BLVRA monoclonal antibodyBovine
GM-Tg-equg-T37046-Ab-1/ GM-Tg-equg-T37046-Ab-2Anti-Equine BLVRA monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T37046-Ab-1/ GM-Tg-hg-T37046-Ab-2; GM-Tg-rg-T37046-Ab-1/ GM-Tg-rg-T37046-Ab-2;
GM-Tg-mg-T37046-Ab-1/ GM-Tg-mg-T37046-Ab-2; GM-Tg-cynog-T37046-Ab-1/ GM-Tg-cynog-T37046-Ab-2;
GM-Tg-felg-T37046-Ab-1/ GM-Tg-felg-T37046-Ab-2; GM-Tg-cang-T37046-Ab-1/ GM-Tg-cang-T37046-Ab-2;
GM-Tg-bovg-T37046-Ab-1/ GM-Tg-bovg-T37046-Ab-2; GM-Tg-equg-T37046-Ab-1/ GM-Tg-equg-T37046-Ab-2
Products NameAnti-BLVRA monoclonal antibody
Formatmab
Target NameBLVRA
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-BLVRA monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T37046-Ag-1Recombinant multi-species BIEA/ BLVRA/ BLVR protein
    ORF Viral VectorpGMLP005044human BLVRA Lentivirus plasmid
    ORF Viral VectorvGMLP005044human BLVRA Lentivirus particle


    Target information

    Target IDGM-T37046
    Target NameBLVRA
    Gene ID644,109778,116599,700980,475867,101088735,504596,100064761
    Gene Symbol and Synonyms0610006A11Rik,2500001N03Rik,BLVR,BLVRA,BVR,BVRA
    Uniprot AccessionP53004,P46844
    Uniprot Entry NameBIEA_HUMAN,BIEA_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseBreast Cancer
    Gene EnsemblENSG00000106605
    Target ClassificationN/A

    The target: BLVRA, gene name: BLVRA, also named as BLVR, BVR, BVRA. The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.