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Anti-GLUL monoclonal antibody
Pre-made anti-GLUL monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to GLUL/GLUL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T37735-Ab-1/ GM-Tg-hg-T37735-Ab-2 | Anti-Human GLUL monoclonal antibody | Human |
| GM-Tg-rg-T37735-Ab-1/ GM-Tg-rg-T37735-Ab-2 | Anti-Rat GLUL monoclonal antibody | Rat |
| GM-Tg-mg-T37735-Ab-1/ GM-Tg-mg-T37735-Ab-2 | Anti-Mouse GLUL monoclonal antibody | Mouse |
| GM-Tg-cynog-T37735-Ab-1/ GM-Tg-cynog-T37735-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GLUL monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T37735-Ab-1/ GM-Tg-felg-T37735-Ab-2 | Anti-Feline GLUL monoclonal antibody | Feline |
| GM-Tg-cang-T37735-Ab-1/ GM-Tg-cang-T37735-Ab-2 | Anti-Canine GLUL monoclonal antibody | Canine |
| GM-Tg-bovg-T37735-Ab-1/ GM-Tg-bovg-T37735-Ab-2 | Anti-Bovine GLUL monoclonal antibody | Bovine |
| GM-Tg-equg-T37735-Ab-1/ GM-Tg-equg-T37735-Ab-2 | Anti-Equine GLUL monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T37735-Ab-1/ GM-Tg-hg-T37735-Ab-2; GM-Tg-rg-T37735-Ab-1/ GM-Tg-rg-T37735-Ab-2; GM-Tg-mg-T37735-Ab-1/ GM-Tg-mg-T37735-Ab-2; GM-Tg-cynog-T37735-Ab-1/ GM-Tg-cynog-T37735-Ab-2; GM-Tg-felg-T37735-Ab-1/ GM-Tg-felg-T37735-Ab-2; GM-Tg-cang-T37735-Ab-1/ GM-Tg-cang-T37735-Ab-2; GM-Tg-bovg-T37735-Ab-1/ GM-Tg-bovg-T37735-Ab-2; GM-Tg-equg-T37735-Ab-1/ GM-Tg-equg-T37735-Ab-2 |
| Products Name | Anti-GLUL monoclonal antibody |
| Format | mab |
| Target Name | GLUL |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-GLUL monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T37735-Ag-1 | Recombinant multi-species GLNA/ GLUL/ GLNS protein |
| ORF Viral Vector | pGMLP002104 | human GLUL Lentivirus plasmid |
| ORF Viral Vector | vGMLP002104 | human GLUL Lentivirus particle |
| ORF Viral Vector | pGMLPm001500 | mouse Glul Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001500 | mouse Glul Lentivirus particle |
Target information
| Target ID | GM-T37735 |
| Target Name | GLUL |
| Gene ID | 2752,14645,24957,715952,403443,101093325,281199,100054716 |
| Gene Symbol and Synonyms | GLNS,GLUL,GS,PIG43,PIG59 |
| Uniprot Accession | P15104,P09606,Q8HZM5,P15103 |
| Uniprot Entry Name | GLNA_HUMAN,GLNA_RAT,GLNA_CANLF,GLNA_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000135821 |
| Target Classification | N/A |
The target: GLUL, gene name: GLUL, also named as GLNS, GS, PIG43, PIG59. The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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