
Anti-CAC1B/ CACNA1B/ BIII antibody for FACS & in-vivo assay| GMab
Cat No.: GM-Tg-hg-T38338-Ab
Pre-made anti-CACNA1B benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CACNA1B mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: CACNA1B, gene name: CACNA1B, also named as BIII, CACNL1A5, CACNN, Cav2.2, DYT23. The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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Catalog No. | List Price (In USD) | Discount Price (In USD) | Qty (Quantity) | Sum (In USD) |
---|---|---|---|---|
GM-Tg-hg-T38338-Ab-1-1mg | 5150 | 3090 | ||
GM-Tg-hg-T38338-Ab-1-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-T38338-Ab-1-100mg | Inquiry | Inquiry | GM-Tg-hg-T38338-Ab-2-1mg | 5150 | 3090 |
GM-Tg-hg-T38338-Ab-2-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-T38338-Ab-2-100mg | Inquiry | Inquiry | GM-Tg-hg-T38338-Ab-xmg | Inquiry | Inquiry |
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Catalog No. | GM-Tg-hg-T38338-Ab-1, GM-Tg-hg-T38338-Ab-2 |
Products Name | Anti-CACNA1B monoclonal antibody |
Format | mab |
Target Name | CACNA1B |
Gene ID | CACNA1B |
Gene Name | CACNA1B |
Gene Alias | BIII, CACNL1A5, CACNN, Cav2.2, DYT23 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
Derivation (species) | Mouse |
Species Reactivity | Human(H) |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-CACNA1B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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