Anti-CAC1B/ CACNA1B/ BIII monoclonal antibody

Anti-CAC1B/ CACNA1B/ BIII antibody for FACS & in-vivo assay

Target products collectionGo to CACNA1B/CACNA1B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T38338-Ab-1/ GM-Tg-hg-T38338-Ab-2Anti-Human CACNA1B monoclonal antibodyHuman
GM-Tg-rg-T38338-Ab-1/ GM-Tg-rg-T38338-Ab-2Anti-Rat CACNA1B monoclonal antibodyRat
GM-Tg-mg-T38338-Ab-1/ GM-Tg-mg-T38338-Ab-2Anti-Mouse CACNA1B monoclonal antibodyMouse
GM-Tg-cynog-T38338-Ab-1/ GM-Tg-cynog-T38338-Ab-2Anti-Cynomolgus/ Rhesus macaque CACNA1B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T38338-Ab-1/ GM-Tg-felg-T38338-Ab-2Anti-Feline CACNA1B monoclonal antibodyFeline
GM-Tg-cang-T38338-Ab-1/ GM-Tg-cang-T38338-Ab-2Anti-Canine CACNA1B monoclonal antibodyCanine
GM-Tg-bovg-T38338-Ab-1/ GM-Tg-bovg-T38338-Ab-2Anti-Bovine CACNA1B monoclonal antibodyBovine
GM-Tg-equg-T38338-Ab-1/ GM-Tg-equg-T38338-Ab-2Anti-Equine CACNA1B monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T38338-Ab-1/ GM-Tg-hg-T38338-Ab-2; GM-Tg-rg-T38338-Ab-1/ GM-Tg-rg-T38338-Ab-2;
GM-Tg-mg-T38338-Ab-1/ GM-Tg-mg-T38338-Ab-2; GM-Tg-cynog-T38338-Ab-1/ GM-Tg-cynog-T38338-Ab-2;
GM-Tg-felg-T38338-Ab-1/ GM-Tg-felg-T38338-Ab-2; GM-Tg-cang-T38338-Ab-1/ GM-Tg-cang-T38338-Ab-2;
GM-Tg-bovg-T38338-Ab-1/ GM-Tg-bovg-T38338-Ab-2; GM-Tg-equg-T38338-Ab-1/ GM-Tg-equg-T38338-Ab-2
Products NameAnti-CACNA1B monoclonal antibody
Target NameCACNA1B
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-CACNA1B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CAC1B/ CACNA1B/ BIII VLP (virus-like particle) (Products Developing)

    Target information

    Target IDGM-T38338
    Target NameCACNA1B
    Gene ID774,12287,257648,721452,480660,101087362,282410,100058760
    Gene Symbol and Synonymsalpha(1B),BIII,CACNA1B,CACNL1A5,CACNN,Cav2.2,Cchn1a,DYT23,NEDNEH
    Uniprot AccessionQ00975,Q02294
    Uniprot Entry NameCAC1B_HUMAN,CAC1B_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    Gene EnsemblENSG00000148408
    Target ClassificationIon Channel

    The target: CACNA1B, gene name: CACNA1B, also named as BIII, CACNL1A5, CACNN, Cav2.2, DYT23. The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.