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Anti-ADA2B/ ADRA2B/ ADRA2L1 monoclonal antibody
Anti-ADA2B/ ADRA2B/ ADRA2L1 antibody for FACS & in-vivo assay
Go to ADRA2B/ADRA2B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T41580-Ab-1/ GM-Tg-hg-T41580-Ab-2 | Anti-Human ADRA2B monoclonal antibody | Human |
| GM-Tg-rg-T41580-Ab-1/ GM-Tg-rg-T41580-Ab-2 | Anti-Rat ADRA2B monoclonal antibody | Rat |
| GM-Tg-mg-T41580-Ab-1/ GM-Tg-mg-T41580-Ab-2 | Anti-Mouse ADRA2B monoclonal antibody | Mouse |
| GM-Tg-cynog-T41580-Ab-1/ GM-Tg-cynog-T41580-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ADRA2B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T41580-Ab-1/ GM-Tg-felg-T41580-Ab-2 | Anti-Feline ADRA2B monoclonal antibody | Feline |
| GM-Tg-cang-T41580-Ab-1/ GM-Tg-cang-T41580-Ab-2 | Anti-Canine ADRA2B monoclonal antibody | Canine |
| GM-Tg-bovg-T41580-Ab-1/ GM-Tg-bovg-T41580-Ab-2 | Anti-Bovine ADRA2B monoclonal antibody | Bovine |
| GM-Tg-equg-T41580-Ab-1/ GM-Tg-equg-T41580-Ab-2 | Anti-Equine ADRA2B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T41580-Ab-1/ GM-Tg-hg-T41580-Ab-2; GM-Tg-rg-T41580-Ab-1/ GM-Tg-rg-T41580-Ab-2; GM-Tg-mg-T41580-Ab-1/ GM-Tg-mg-T41580-Ab-2; GM-Tg-cynog-T41580-Ab-1/ GM-Tg-cynog-T41580-Ab-2; GM-Tg-felg-T41580-Ab-1/ GM-Tg-felg-T41580-Ab-2; GM-Tg-cang-T41580-Ab-1/ GM-Tg-cang-T41580-Ab-2; GM-Tg-bovg-T41580-Ab-1/ GM-Tg-bovg-T41580-Ab-2; GM-Tg-equg-T41580-Ab-1/ GM-Tg-equg-T41580-Ab-2 |
| Products Name | Anti-ADRA2B monoclonal antibody |
| Format | mab |
| Target Name | ADRA2B |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ADRA2B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ADA2B/ ADRA2B/ ADRA2L1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003709 | human ADRA2B Lentivirus particle |
| ORF Viral Vector | pGMLP003709 | human ADRA2B Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004977 | mouse Adra2b Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004977 | mouse Adra2b Lentivirus particle |
Target information
| Target ID | GM-T41580 |
| Target Name | ADRA2B |
| Gene ID | 151,11552,24174,694825,100855976,101090432,516422,100051684 |
| Gene Symbol and Synonyms | a2b-AR,Adra-2b,ADRA2B,ADRA2L1,ADRA2RL1,adrab2,ADRARL1,alpha-2BAR,alpha2-C2,alpha2B,ALPHA2BAR,FAME2,[a]2B |
| Uniprot Accession | P18089,P19328,O77700,O77721 |
| Uniprot Entry Name | ADA2B_HUMAN,ADA2B_RAT,ADA2B_BOVIN,ADA2B_HORSE |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000274286 |
| Target Classification | N/A |
The target: ADRA2B, gene name: ADRA2B, also named as ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, FAME2, alpha-2BAR. This intronless gene encodes a seven-pass transmembrane protein. This protein is a member of a subfamily of G protein-coupled receptors that regulate neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. [provided by RefSeq, Apr 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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