Anti-GLUC/ GCG/ GLP-1 functional antibody

Anti-GLUC/ GCG/ GLP-1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to GCG/GCG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T44919-Ab-1/ GM-Tg-hg-T44919-Ab-2Anti-Human GCG monoclonal antibodyHuman
GM-Tg-rg-T44919-Ab-1/ GM-Tg-rg-T44919-Ab-2Anti-Rat GCG monoclonal antibodyRat
GM-Tg-mg-T44919-Ab-1/ GM-Tg-mg-T44919-Ab-2Anti-Mouse GCG monoclonal antibodyMouse
GM-Tg-cynog-T44919-Ab-1/ GM-Tg-cynog-T44919-Ab-2Anti-Cynomolgus/ Rhesus macaque GCG monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T44919-Ab-1/ GM-Tg-felg-T44919-Ab-2Anti-Feline GCG monoclonal antibodyFeline
GM-Tg-cang-T44919-Ab-1/ GM-Tg-cang-T44919-Ab-2Anti-Canine GCG monoclonal antibodyCanine
GM-Tg-bovg-T44919-Ab-1/ GM-Tg-bovg-T44919-Ab-2Anti-Bovine GCG monoclonal antibodyBovine
GM-Tg-equg-T44919-Ab-1/ GM-Tg-equg-T44919-Ab-2Anti-Equine GCG monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T44919-Ab-1/ GM-Tg-hg-T44919-Ab-2; GM-Tg-rg-T44919-Ab-1/ GM-Tg-rg-T44919-Ab-2;
GM-Tg-mg-T44919-Ab-1/ GM-Tg-mg-T44919-Ab-2; GM-Tg-cynog-T44919-Ab-1/ GM-Tg-cynog-T44919-Ab-2;
GM-Tg-felg-T44919-Ab-1/ GM-Tg-felg-T44919-Ab-2; GM-Tg-cang-T44919-Ab-1/ GM-Tg-cang-T44919-Ab-2;
GM-Tg-bovg-T44919-Ab-1/ GM-Tg-bovg-T44919-Ab-2; GM-Tg-equg-T44919-Ab-1/ GM-Tg-equg-T44919-Ab-2
Products NameAnti-GCG monoclonal antibody
Target NameGCG
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-GCG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T44919-Ag-1Recombinant multi-species GLUC/ GCG/ GLP-1 protein
    ORF Viral VectorvGMLP002234human GCG Lentivirus particle
    ORF Viral VectorpGMLP002234human GCG Lentivirus plasmid
    ORF Viral VectorpGMLPm000645mouse Gcg Lentivirus plasmid
    ORF Viral VectorvGMLPm000645mouse Gcg Lentivirus particle

    Target information

    Target IDGM-T44919
    Target NameGCG
    Gene ID2641,14526,24952,705508,403571,101097825,280802,100051551
    Gene Symbol and SynonymsGCG,GLP-1,GLP-2,GLP1,GLP2,Glu,GRPP,PPG
    Uniprot AccessionP01275,P06883,P29794,P01272
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryTherapeutics Target
    Gene EnsemblENSG00000115263
    Target ClassificationN/A

    The target: GCG, gene name: GCG, also named as GLP-1, GLP1, GLP2, GRPP. The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.