Anti-DRD5/ D5R/ DBDR monoclonal antibody

Anti-DRD5/ D5R/ DBDR antibody for FACS & in-vivo assay

Target products collectionGo to D5R/DRD5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T46828-Ab-1/ GM-Tg-hg-T46828-Ab-2Anti-Human D5R/DRD5 monoclonal antibodyHuman
GM-Tg-rg-T46828-Ab-1/ GM-Tg-rg-T46828-Ab-2Anti-Rat D5R/DRD5 monoclonal antibodyRat
GM-Tg-mg-T46828-Ab-1/ GM-Tg-mg-T46828-Ab-2Anti-Mouse D5R/DRD5 monoclonal antibodyMouse
GM-Tg-cynog-T46828-Ab-1/ GM-Tg-cynog-T46828-Ab-2Anti-Cynomolgus/ Rhesus macaque D5R/DRD5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T46828-Ab-1/ GM-Tg-felg-T46828-Ab-2Anti-Feline D5R/DRD5 monoclonal antibodyFeline
GM-Tg-cang-T46828-Ab-1/ GM-Tg-cang-T46828-Ab-2Anti-Canine D5R/DRD5 monoclonal antibodyCanine
GM-Tg-bovg-T46828-Ab-1/ GM-Tg-bovg-T46828-Ab-2Anti-Bovine D5R/DRD5 monoclonal antibodyBovine
GM-Tg-equg-T46828-Ab-1/ GM-Tg-equg-T46828-Ab-2Anti-Equine D5R/DRD5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T46828-Ab-1/ GM-Tg-hg-T46828-Ab-2; GM-Tg-rg-T46828-Ab-1/ GM-Tg-rg-T46828-Ab-2;
GM-Tg-mg-T46828-Ab-1/ GM-Tg-mg-T46828-Ab-2; GM-Tg-cynog-T46828-Ab-1/ GM-Tg-cynog-T46828-Ab-2;
GM-Tg-felg-T46828-Ab-1/ GM-Tg-felg-T46828-Ab-2; GM-Tg-cang-T46828-Ab-1/ GM-Tg-cang-T46828-Ab-2;
GM-Tg-bovg-T46828-Ab-1/ GM-Tg-bovg-T46828-Ab-2; GM-Tg-equg-T46828-Ab-1/ GM-Tg-equg-T46828-Ab-2
Products NameAnti-D5R/DRD5 monoclonal antibody
Formatmab
Target NameD5R
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-D5R benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species DRD5/ D5R/ DBDR VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T46828
    Target NameD5R
    Gene ID1816,13492,25195,712862,488824,101091278,526221,100069604
    Gene Symbol and SynonymsD1B,D5R,DBDR,Drd-5,DRD1B,DRD1L2,DRD5,Gpcr1
    Uniprot AccessionP21918,P25115,Q95195,Q95137
    Uniprot Entry NameDRD5_HUMAN,DRD5_MACMU,DRD5_RAT,DRD5_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000169676
    Target ClassificationGPCR

    The target: D5R, gene name: DRD5, also named as DBDR, DRD1B, DRD1L2. This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.