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Anti-SECR/ SCT functional antibody
Anti-SECR/ SCT functional antibody for cell culture, ELISA & in-vivo assay
Go to SCT/SCT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T46904-Ab-1/ GM-Tg-hg-T46904-Ab-2 | Anti-Human SCT monoclonal antibody | Human |
| GM-Tg-rg-T46904-Ab-1/ GM-Tg-rg-T46904-Ab-2 | Anti-Rat SCT monoclonal antibody | Rat |
| GM-Tg-mg-T46904-Ab-1/ GM-Tg-mg-T46904-Ab-2 | Anti-Mouse SCT monoclonal antibody | Mouse |
| GM-Tg-cynog-T46904-Ab-1/ GM-Tg-cynog-T46904-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SCT monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T46904-Ab-1/ GM-Tg-felg-T46904-Ab-2 | Anti-Feline SCT monoclonal antibody | Feline |
| GM-Tg-cang-T46904-Ab-1/ GM-Tg-cang-T46904-Ab-2 | Anti-Canine SCT monoclonal antibody | Canine |
| GM-Tg-bovg-T46904-Ab-1/ GM-Tg-bovg-T46904-Ab-2 | Anti-Bovine SCT monoclonal antibody | Bovine |
| GM-Tg-equg-T46904-Ab-1/ GM-Tg-equg-T46904-Ab-2 | Anti-Equine SCT monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T46904-Ab-1/ GM-Tg-hg-T46904-Ab-2; GM-Tg-rg-T46904-Ab-1/ GM-Tg-rg-T46904-Ab-2; GM-Tg-mg-T46904-Ab-1/ GM-Tg-mg-T46904-Ab-2; GM-Tg-cynog-T46904-Ab-1/ GM-Tg-cynog-T46904-Ab-2; GM-Tg-felg-T46904-Ab-1/ GM-Tg-felg-T46904-Ab-2; GM-Tg-cang-T46904-Ab-1/ GM-Tg-cang-T46904-Ab-2; GM-Tg-bovg-T46904-Ab-1/ GM-Tg-bovg-T46904-Ab-2; GM-Tg-equg-T46904-Ab-1/ GM-Tg-equg-T46904-Ab-2 |
| Products Name | Anti-SCT monoclonal antibody |
| Format | mab |
| Target Name | SCT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SCT benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T46904-Ag-1 | Recombinant multi-species SECR/ SCT protein |
| ORF Viral Vector | pGMLP004971 | human SCT Lentivirus plasmid |
| ORF Viral Vector | vGMLP004971 | human SCT Lentivirus particle |
| ORF Viral Vector | pGMLPm000633 | mouse Sct Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000633 | mouse Sct Lentivirus particle |
Target information
| Target ID | GM-T46904 |
| Target Name | SCT |
| Gene ID | 6343,20287,24769,114672195,119864200,109492260,104976311,100630455 |
| Gene Symbol and Synonyms | SCT,Secr |
| Uniprot Accession | P09683,P11384,P09910,P63296 |
| Uniprot Entry Name | SECR_HUMAN,SECR_RAT,SECR_CANLF,SECR_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000070031 |
| Target Classification | N/A |
The target: SCT, gene name: SCT, also named as . This gene encodes a member of the glucagon family of peptides. The encoded preproprotein is secreted by endocrine S cells in the proximal small intestinal mucosa as a prohormone, then proteolytically processed to generate the mature peptide hormone. The release of this active peptide hormone is stimulated by either fatty acids or acidic pH in the duodenum. This hormone stimulates the secretion of bile and bicarbonate in the duodenum, pancreatic and biliary ducts. [provided by RefSeq, Feb 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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