- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-HB monoclonal antibody
Pre-made anti-HB monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to HB/HBA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T49493-Ab-1/ GM-Tg-hg-T49493-Ab-2 | Anti-Human HB/HBA2 monoclonal antibody | Human |
| GM-Tg-rg-T49493-Ab-1/ GM-Tg-rg-T49493-Ab-2 | Anti-Rat HB/HBA2 monoclonal antibody | Rat |
| GM-Tg-mg-T49493-Ab-1/ GM-Tg-mg-T49493-Ab-2 | Anti-Mouse HB/HBA2 monoclonal antibody | Mouse |
| GM-Tg-cynog-T49493-Ab-1/ GM-Tg-cynog-T49493-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HB/HBA2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T49493-Ab-1/ GM-Tg-felg-T49493-Ab-2 | Anti-Feline HB/HBA2 monoclonal antibody | Feline |
| GM-Tg-cang-T49493-Ab-1/ GM-Tg-cang-T49493-Ab-2 | Anti-Canine HB/HBA2 monoclonal antibody | Canine |
| GM-Tg-bovg-T49493-Ab-1/ GM-Tg-bovg-T49493-Ab-2 | Anti-Bovine HB/HBA2 monoclonal antibody | Bovine |
| GM-Tg-equg-T49493-Ab-1/ GM-Tg-equg-T49493-Ab-2 | Anti-Equine HB/HBA2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T49493-Ab-1/ GM-Tg-hg-T49493-Ab-2; GM-Tg-rg-T49493-Ab-1/ GM-Tg-rg-T49493-Ab-2; GM-Tg-mg-T49493-Ab-1/ GM-Tg-mg-T49493-Ab-2; GM-Tg-cynog-T49493-Ab-1/ GM-Tg-cynog-T49493-Ab-2; GM-Tg-felg-T49493-Ab-1/ GM-Tg-felg-T49493-Ab-2; GM-Tg-cang-T49493-Ab-1/ GM-Tg-cang-T49493-Ab-2; GM-Tg-bovg-T49493-Ab-1/ GM-Tg-bovg-T49493-Ab-2; GM-Tg-equg-T49493-Ab-1/ GM-Tg-equg-T49493-Ab-2 |
| Products Name | Anti-HB/HBA2 monoclonal antibody |
| Format | mab |
| Target Name | HB |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-HB monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T49493-Ag-1 | Recombinant multi-species HBA/ HB/ HBA2 protein |
| ORF Viral Vector | vGMLP000959 | human HBA2 Lentivirus particle |
| ORF Viral Vector | pGMLP000959 | human HBA2 Lentivirus plasmid |
Target information
| Target ID | GM-T49493 |
| Target Name | HB |
| Gene ID | 3040 |
| Gene Symbol and Synonyms | ECYT7,HBA-T2,HBA2,HBH |
| Uniprot Accession | P69905 |
| Uniprot Entry Name | HBA_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Alzheimer's Disease, congestive heart failure, Diabetes type-2 |
| Gene Ensembl | ENSG00000188536 |
| Target Classification | N/A |
The target: HB, gene name: HBA2, also named as ECYT7, HBA-T2, HBH. The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
