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Anti-LIPE monoclonal antibody
Pre-made anti-LIPE monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to LIPE/LIPE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T55689-Ab-1/ GM-Tg-hg-T55689-Ab-2 | Anti-Human LIPE monoclonal antibody | Human |
| GM-Tg-rg-T55689-Ab-1/ GM-Tg-rg-T55689-Ab-2 | Anti-Rat LIPE monoclonal antibody | Rat |
| GM-Tg-mg-T55689-Ab-1/ GM-Tg-mg-T55689-Ab-2 | Anti-Mouse LIPE monoclonal antibody | Mouse |
| GM-Tg-cynog-T55689-Ab-1/ GM-Tg-cynog-T55689-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LIPE monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T55689-Ab-1/ GM-Tg-felg-T55689-Ab-2 | Anti-Feline LIPE monoclonal antibody | Feline |
| GM-Tg-cang-T55689-Ab-1/ GM-Tg-cang-T55689-Ab-2 | Anti-Canine LIPE monoclonal antibody | Canine |
| GM-Tg-bovg-T55689-Ab-1/ GM-Tg-bovg-T55689-Ab-2 | Anti-Bovine LIPE monoclonal antibody | Bovine |
| GM-Tg-equg-T55689-Ab-1/ GM-Tg-equg-T55689-Ab-2 | Anti-Equine LIPE monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T55689-Ab-1/ GM-Tg-hg-T55689-Ab-2; GM-Tg-rg-T55689-Ab-1/ GM-Tg-rg-T55689-Ab-2; GM-Tg-mg-T55689-Ab-1/ GM-Tg-mg-T55689-Ab-2; GM-Tg-cynog-T55689-Ab-1/ GM-Tg-cynog-T55689-Ab-2; GM-Tg-felg-T55689-Ab-1/ GM-Tg-felg-T55689-Ab-2; GM-Tg-cang-T55689-Ab-1/ GM-Tg-cang-T55689-Ab-2; GM-Tg-bovg-T55689-Ab-1/ GM-Tg-bovg-T55689-Ab-2; GM-Tg-equg-T55689-Ab-1/ GM-Tg-equg-T55689-Ab-2 |
| Products Name | Anti-LIPE monoclonal antibody |
| Format | mab |
| Target Name | LIPE |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-LIPE monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T55689-Ag-1 | Recombinant multi-species LIPS/ LIPE/ AOMS4 protein |
Target information
| Target ID | GM-T55689 |
| Target Name | LIPE |
| Gene ID | 3991,16890,25330,707997,403607,751818,286879,100069598 |
| Gene Symbol and Synonyms | 4933403G17Rik,AOMS4,FPLD6,HSL,LHS,LIPE,REH |
| Uniprot Accession | Q05469,P15304,P16386 |
| Uniprot Entry Name | LIPS_HUMAN,LIPS_RAT,LIPS_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000079435 |
| Target Classification | N/A |
The target: LIPE, gene name: LIPE, also named as AOMS4, FPLD6, HSL, LHS. The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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