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Anti-AMD1 monoclonal antibody
Pre-made anti-AMD1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to AMD1/AMD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T55922-Ab-1/ GM-Tg-hg-T55922-Ab-2 | Anti-Human AMD1 monoclonal antibody | Human |
| GM-Tg-rg-T55922-Ab-1/ GM-Tg-rg-T55922-Ab-2 | Anti-Rat AMD1 monoclonal antibody | Rat |
| GM-Tg-mg-T55922-Ab-1/ GM-Tg-mg-T55922-Ab-2 | Anti-Mouse AMD1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T55922-Ab-1/ GM-Tg-cynog-T55922-Ab-2 | Anti-Cynomolgus/ Rhesus macaque AMD1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T55922-Ab-1/ GM-Tg-felg-T55922-Ab-2 | Anti-Feline AMD1 monoclonal antibody | Feline |
| GM-Tg-cang-T55922-Ab-1/ GM-Tg-cang-T55922-Ab-2 | Anti-Canine AMD1 monoclonal antibody | Canine |
| GM-Tg-bovg-T55922-Ab-1/ GM-Tg-bovg-T55922-Ab-2 | Anti-Bovine AMD1 monoclonal antibody | Bovine |
| GM-Tg-equg-T55922-Ab-1/ GM-Tg-equg-T55922-Ab-2 | Anti-Equine AMD1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T55922-Ab-1/ GM-Tg-hg-T55922-Ab-2; GM-Tg-rg-T55922-Ab-1/ GM-Tg-rg-T55922-Ab-2; GM-Tg-mg-T55922-Ab-1/ GM-Tg-mg-T55922-Ab-2; GM-Tg-cynog-T55922-Ab-1/ GM-Tg-cynog-T55922-Ab-2; GM-Tg-felg-T55922-Ab-1/ GM-Tg-felg-T55922-Ab-2; GM-Tg-cang-T55922-Ab-1/ GM-Tg-cang-T55922-Ab-2; GM-Tg-bovg-T55922-Ab-1/ GM-Tg-bovg-T55922-Ab-2; GM-Tg-equg-T55922-Ab-1/ GM-Tg-equg-T55922-Ab-2 |
| Products Name | Anti-AMD1 monoclonal antibody |
| Format | mab |
| Target Name | AMD1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-AMD1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T55922-Ag-1 | Recombinant multi-species DCAM/ AMD1/ ADOMETDC protein |
| ORF Viral Vector | vGMLP003549 | human AMD1 Lentivirus particle |
| ORF Viral Vector | pGMLP003549 | human AMD1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002153 | mouse Amd1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003992 | mouse Amd1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002153 | mouse Amd1 Lentivirus particle |
| ORF Viral Vector | vGMLPm003992 | mouse Amd1 Lentivirus particle |
Target information
| Target ID | GM-T55922 |
| Target Name | AMD1 |
| Gene ID | 262,11702,81640,698042,481960,101084109,280997,100072355 |
| Gene Symbol and Synonyms | ADOMETDC,adoMetDC1,AMD,Amd-1,AMD1,Amd1a,Amd1b,SAMDC,SAMDC 1 |
| Uniprot Accession | P17707,P17708,P50243 |
| Uniprot Entry Name | DCAM_HUMAN,DCAM_RAT,DCAM_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000123505 |
| Target Classification | N/A |
The target: AMD1, gene name: AMD1, also named as ADOMETDC, AMD, SAMDC. This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y. [provided by RefSeq, Dec 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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