Anti-CD117/c-Kit/KIT monoclonal antibody
The Alternative Names of target: CD117, c-Kit, KIT,Mast/stem cell growth factor receptor Kit,SCFR,Piebald trait protein (PBT), Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog,PBT,SCFR,C-Kit,CD117,MASTC
Pre-made anti-CD117/c-Kit/KIT monoclonal antibody (mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T57700-Ab-1/ GM-Tg-hg-T57700-Ab-2 | Anti-Human CD117/c-Kit/KIT monoclonal antibody | Human |
GM-Tg-rg-T57700-Ab-1/ GM-Tg-rg-T57700-Ab-2 | Anti-Rat CD117/c-Kit/KIT monoclonal antibody | Rat |
GM-Tg-mg-T57700-Ab-1/ GM-Tg-mg-T57700-Ab-2 | Anti-Mouse CD117/c-Kit/KIT monoclonal antibody | Mouse |
GM-Tg-cynog-T57700-Ab-1/ GM-Tg-cynog-T57700-Ab-2 | Anti-Cynomolgus/Rhesus macaque CD117/c-Kit/KIT monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T57700-Ab-1/ GM-Tg-felg-T57700-Ab-2 | Anti-Feline CD117/c-Kit/KIT monoclonal antibody | Feline |
GM-Tg-cang-T57700-Ab-1/ GM-Tg-cang-T57700-Ab-2 | Anti-Canine CD117/c-Kit/KIT monoclonal antibody | Canine |
GM-Tg-bovg-T57700-Ab-1/ GM-Tg-bovg-T57700-Ab-2 | Anti-Bovine CD117/c-Kit/KIT monoclonal antibody | Bovine |
GM-Tg-equg-T57700-Ab-1/ GM-Tg-equg-T57700-Ab-2 | Anti-Equine CD117/c-Kit/KIT monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T57700-Ab-1/ GM-Tg-hg-T57700-Ab-2;
GM-Tg-rg-T57700-Ab-1/ GM-Tg-rg-T57700-Ab-2;
GM-Tg-mg-T57700-Ab-1/ GM-Tg-mg-T57700-Ab-2; GM-Tg-cynog-T57700-Ab-1/ GM-Tg-cynog-T57700-Ab-2; GM-Tg-felg-T57700-Ab-1/ GM-Tg-felg-T57700-Ab-2; GM-Tg-cang-T57700-Ab-1/ GM-Tg-cang-T57700-Ab-2; GM-Tg-bovg-T57700-Ab-1/ GM-Tg-bovg-T57700-Ab-2; GM-Tg-equg-T57700-Ab-1/ GM-Tg-equg-T57700-Ab-2 |
Products Name | Anti-CD117/c-Kit/KIT monoclonal antibody |
Format | mab |
Target Name | CD117/c-Kit/KIT |
Protein Sub-location | Transmembrane Protein |
Category of antibody | Therapeutics Target, Immuno-oncology Target, INN Index |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) |
IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-CD117/c-Kit/KIT monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data/case study
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About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.
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