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Anti-RXRB monoclonal antibody
Pre-made anti-RXRB monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RXRB/RXRB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T60077-Ab-1/ GM-Tg-hg-T60077-Ab-2 | Anti-Human RXRB monoclonal antibody | Human |
| GM-Tg-rg-T60077-Ab-1/ GM-Tg-rg-T60077-Ab-2 | Anti-Rat RXRB monoclonal antibody | Rat |
| GM-Tg-mg-T60077-Ab-1/ GM-Tg-mg-T60077-Ab-2 | Anti-Mouse RXRB monoclonal antibody | Mouse |
| GM-Tg-cynog-T60077-Ab-1/ GM-Tg-cynog-T60077-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RXRB monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T60077-Ab-1/ GM-Tg-felg-T60077-Ab-2 | Anti-Feline RXRB monoclonal antibody | Feline |
| GM-Tg-cang-T60077-Ab-1/ GM-Tg-cang-T60077-Ab-2 | Anti-Canine RXRB monoclonal antibody | Canine |
| GM-Tg-bovg-T60077-Ab-1/ GM-Tg-bovg-T60077-Ab-2 | Anti-Bovine RXRB monoclonal antibody | Bovine |
| GM-Tg-equg-T60077-Ab-1/ GM-Tg-equg-T60077-Ab-2 | Anti-Equine RXRB monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T60077-Ab-1/ GM-Tg-hg-T60077-Ab-2; GM-Tg-rg-T60077-Ab-1/ GM-Tg-rg-T60077-Ab-2; GM-Tg-mg-T60077-Ab-1/ GM-Tg-mg-T60077-Ab-2; GM-Tg-cynog-T60077-Ab-1/ GM-Tg-cynog-T60077-Ab-2; GM-Tg-felg-T60077-Ab-1/ GM-Tg-felg-T60077-Ab-2; GM-Tg-cang-T60077-Ab-1/ GM-Tg-cang-T60077-Ab-2; GM-Tg-bovg-T60077-Ab-1/ GM-Tg-bovg-T60077-Ab-2; GM-Tg-equg-T60077-Ab-1/ GM-Tg-equg-T60077-Ab-2 |
| Products Name | Anti-RXRB monoclonal antibody |
| Format | mab |
| Target Name | RXRB |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RXRB monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T60077-Ag-1 | Recombinant multi-species RXRB/ DAUDI6/ H-2RIIBP protein |
| ORF Viral Vector | pGMLP003968 | human RXRB Lentivirus plasmid |
| ORF Viral Vector | vGMLP003968 | human RXRB Lentivirus particle |
Target information
| Target ID | GM-T60077 |
| Target Name | RXRB |
| Gene ID | 6257,20182,361801,717368,481735,101085801,504943,100061303 |
| Gene Symbol and Synonyms | DAUDI6,H-2RIIBP,NR2B2,RCoR-1,Rub,RXR-beta,RXRB,RXRbeta |
| Uniprot Accession | P28702,P49743,Q5TJF7 |
| Uniprot Entry Name | RXRB_HUMAN,RXRB_RAT,RXRB_CANLF |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000204231 |
| Target Classification | N/A |
The target: RXRB, gene name: RXRB, also named as DAUDI6, H-2RIIBP, NR2B2, RCoR-1. This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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