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Anti-CD1A/ CD1/ FCB6 monoclonal antibody
Anti-CD1A/ CD1/ FCB6 antibody for FACS & in-vivo assay
Go to CD1A/CD1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T60433-Ab-1/ GM-Tg-hg-T60433-Ab-2 | Anti-Human CD1A monoclonal antibody | Human |
| GM-Tg-rg-T60433-Ab-1/ GM-Tg-rg-T60433-Ab-2 | Anti-Rat CD1A monoclonal antibody | Rat |
| GM-Tg-mg-T60433-Ab-1/ GM-Tg-mg-T60433-Ab-2 | Anti-Mouse CD1A monoclonal antibody | Mouse |
| GM-Tg-cynog-T60433-Ab-1/ GM-Tg-cynog-T60433-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CD1A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T60433-Ab-1/ GM-Tg-felg-T60433-Ab-2 | Anti-Feline CD1A monoclonal antibody | Feline |
| GM-Tg-cang-T60433-Ab-1/ GM-Tg-cang-T60433-Ab-2 | Anti-Canine CD1A monoclonal antibody | Canine |
| GM-Tg-bovg-T60433-Ab-1/ GM-Tg-bovg-T60433-Ab-2 | Anti-Bovine CD1A monoclonal antibody | Bovine |
| GM-Tg-equg-T60433-Ab-1/ GM-Tg-equg-T60433-Ab-2 | Anti-Equine CD1A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T60433-Ab-1/ GM-Tg-hg-T60433-Ab-2; GM-Tg-rg-T60433-Ab-1/ GM-Tg-rg-T60433-Ab-2; GM-Tg-mg-T60433-Ab-1/ GM-Tg-mg-T60433-Ab-2; GM-Tg-cynog-T60433-Ab-1/ GM-Tg-cynog-T60433-Ab-2; GM-Tg-felg-T60433-Ab-1/ GM-Tg-felg-T60433-Ab-2; GM-Tg-cang-T60433-Ab-1/ GM-Tg-cang-T60433-Ab-2; GM-Tg-bovg-T60433-Ab-1/ GM-Tg-bovg-T60433-Ab-2; GM-Tg-equg-T60433-Ab-1/ GM-Tg-equg-T60433-Ab-2 |
| Products Name | Anti-CD1A monoclonal antibody |
| Format | mab |
| Target Name | CD1A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CD1A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species CD1A/ CD1/ FCB6 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP004956 | human CD1A Lentivirus particle |
| ORF Viral Vector | pGMLP004956 | human CD1A Lentivirus plasmid |
Target information
| Target ID | GM-T60433 |
| Target Name | CD1A |
| Gene ID | 909,698438 |
| Gene Symbol and Synonyms | CD1,CD1A,FCB6,HTA1,R4,T6 |
| Uniprot Accession | P06126 |
| Uniprot Entry Name | CD1A_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000158477 |
| Target Classification | Checkpoint-Immuno Oncology |
The target: CD1A, gene name: CD1A, also named as CD1, FCB6, HTA1, R4, T6. This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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