Anti-ALBU/ ALB/ HSA functional antibody

Anti-ALBU/ ALB/ HSA functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ALB/ALB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T63068-Ab-1/ GM-Tg-hg-T63068-Ab-2Anti-Human ALB monoclonal antibodyHuman
GM-Tg-rg-T63068-Ab-1/ GM-Tg-rg-T63068-Ab-2Anti-Rat ALB monoclonal antibodyRat
GM-Tg-mg-T63068-Ab-1/ GM-Tg-mg-T63068-Ab-2Anti-Mouse ALB monoclonal antibodyMouse
GM-Tg-cynog-T63068-Ab-1/ GM-Tg-cynog-T63068-Ab-2Anti-Cynomolgus/ Rhesus macaque ALB monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T63068-Ab-1/ GM-Tg-felg-T63068-Ab-2Anti-Feline ALB monoclonal antibodyFeline
GM-Tg-cang-T63068-Ab-1/ GM-Tg-cang-T63068-Ab-2Anti-Canine ALB monoclonal antibodyCanine
GM-Tg-bovg-T63068-Ab-1/ GM-Tg-bovg-T63068-Ab-2Anti-Bovine ALB monoclonal antibodyBovine
GM-Tg-equg-T63068-Ab-1/ GM-Tg-equg-T63068-Ab-2Anti-Equine ALB monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T63068-Ab-1/ GM-Tg-hg-T63068-Ab-2; GM-Tg-rg-T63068-Ab-1/ GM-Tg-rg-T63068-Ab-2;
GM-Tg-mg-T63068-Ab-1/ GM-Tg-mg-T63068-Ab-2; GM-Tg-cynog-T63068-Ab-1/ GM-Tg-cynog-T63068-Ab-2;
GM-Tg-felg-T63068-Ab-1/ GM-Tg-felg-T63068-Ab-2; GM-Tg-cang-T63068-Ab-1/ GM-Tg-cang-T63068-Ab-2;
GM-Tg-bovg-T63068-Ab-1/ GM-Tg-bovg-T63068-Ab-2; GM-Tg-equg-T63068-Ab-1/ GM-Tg-equg-T63068-Ab-2
Products NameAnti-ALB monoclonal antibody
Formatmab
Target NameALB
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ALB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    BiosimilarGMP-Bios-ab-625Pre-Made Vobarilizumab biosimilar, Bispecific Single Domains (VH-VH'), Anti-IL6R;ALB Antibody: Anti-CD126/HIES5/IL-1Ra/IL-6R/IL-6R-1/IL-6RA/IL6Q/IL6QTL/IL6RA/IL6RQ/gp80;FDAHT/HSA/PRO0883/PRO0903/PRO1341 therapeutic antibody
    BiosimilarGMP-Bios-ab-281Pre-Made Isecarosmab biosimilar, Bispecific Single Domains (VH-VH'), Anti-ADAMTSL5;ALB Antibody: Anti-THSD6;FDAHT/HSA/PRO0883/PRO0903/PRO1341 therapeutic antibody
    BiosimilarGMP-Bios-ab-419Pre-Made Ozoralizumab biosimilar, Bispecific Single Domains (VH-VH'-VH), Anti-TNFA/TNF;ALB Antibody: Anti-DIF/TNF-alpha/TNFSF2/TNLG1F;FDAHT/HSA/PRO0883/PRO0903/PRO1341 therapeutic antibody
    BiosimilarGMP-Bios-INN-996Pre-Made Sonelokimab Biosimilar, Bispecific, Anti-ALB;IL17A/IL17;IL17F Antibody: Anti-FDAHT/HSA/PRO0883/PRO0903/PRO1341;CTLA-8/CTLA8/IL-17A/ILA17;CANDF6/ML-1/ML1 therapeutic antibody
    Target AntigenGM-Tg-g-T63068-Ag-1Recombinant multi-species ALBU/ ALB/ HSA protein
    ORF Viral VectorvGMLP001108human ALB Lentivirus particle
    ORF Viral VectorvGMLP003870human ALB Lentivirus particle
    ORF Viral VectorpGMLP001108human ALB Lentivirus plasmid
    ORF Viral VectorpGMLP003870human ALB Lentivirus plasmid
    ORF Viral VectorpGMLPm003412mouse Alb Lentivirus plasmid
    ORF Viral VectorvGMLPm003412mouse Alb Lentivirus particle


    Target information

    Target IDGM-T63068
    Target NameALB
    Gene ID213,11657,24186,704892,403550,448843,280717,100034206
    Gene Symbol and SynonymsALB,Alb-1,Alb1,Albza,BCL002,CSA,FDAHT,HSA,PRO0883,PRO0903,PRO1341
    Uniprot AccessionP02768,P02770,Q28522,P49822,P49064,P02769,P35747
    Uniprot Entry NameALBU_HUMAN,ALBU_MACMU,ALBU_RAT,ALBU_FELCA,ALBU_CANLF,ALBU_BOVIN,ALBU_HORSE
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryTherapeutics Target, Diagnostics Biomarker, INN Index
    DiseaseNephropathy induced by other drugs, medicaments and biological substances, Acute kidney failure, Asphyxia neonatorum, Calculus of kidney, Congenital occlusion of ureteropelvic junction, Crohn's disease, Diabetic Nephropathy, IgA glomerulonephritis, Nephrotic syndrome, Obstructive sleep apnea (adult) (pediatric), Ovarian cancer, Pre-eclampsia, Pregnant state, Type 2 diabetes mellitus, Type 2 diabetes mellitus with diabetic nephropathy
    Gene EnsemblENSG00000163631
    Target ClassificationN/A

    The target: ALB, gene name: ALB, also named as HSA, PRO0883, PRO0903, PRO1341. This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.