Anti-ALBU/ ALB/ HSA functional antibody
Anti-ALBU/ ALB/ HSA functional antibody for cell culture, ELISA & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T63068-Ab-1/ GM-Tg-hg-T63068-Ab-2 | Anti-Human ALB monoclonal antibody | Human |
GM-Tg-rg-T63068-Ab-1/ GM-Tg-rg-T63068-Ab-2 | Anti-Rat ALB monoclonal antibody | Rat |
GM-Tg-mg-T63068-Ab-1/ GM-Tg-mg-T63068-Ab-2 | Anti-Mouse ALB monoclonal antibody | Mouse |
GM-Tg-cynog-T63068-Ab-1/ GM-Tg-cynog-T63068-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ALB monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T63068-Ab-1/ GM-Tg-felg-T63068-Ab-2 | Anti-Feline ALB monoclonal antibody | Feline |
GM-Tg-cang-T63068-Ab-1/ GM-Tg-cang-T63068-Ab-2 | Anti-Canine ALB monoclonal antibody | Canine |
GM-Tg-bovg-T63068-Ab-1/ GM-Tg-bovg-T63068-Ab-2 | Anti-Bovine ALB monoclonal antibody | Bovine |
GM-Tg-equg-T63068-Ab-1/ GM-Tg-equg-T63068-Ab-2 | Anti-Equine ALB monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T63068-Ab-1/ GM-Tg-hg-T63068-Ab-2; GM-Tg-rg-T63068-Ab-1/ GM-Tg-rg-T63068-Ab-2; GM-Tg-mg-T63068-Ab-1/ GM-Tg-mg-T63068-Ab-2; GM-Tg-cynog-T63068-Ab-1/ GM-Tg-cynog-T63068-Ab-2; GM-Tg-felg-T63068-Ab-1/ GM-Tg-felg-T63068-Ab-2; GM-Tg-cang-T63068-Ab-1/ GM-Tg-cang-T63068-Ab-2; GM-Tg-bovg-T63068-Ab-1/ GM-Tg-bovg-T63068-Ab-2; GM-Tg-equg-T63068-Ab-1/ GM-Tg-equg-T63068-Ab-2 |
Products Name | Anti-ALB monoclonal antibody |
Format | mab |
Target Name | ALB |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-ALB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Target information
Target ID | GM-T63068 |
Target Name | ALB |
Gene ID | 213,11657,24186,704892,403550,448843,280717,100034206 |
Gene Symbol and Synonyms | ALB,Alb-1,Alb1,Albza,BCL002,CSA,FDAHT,HSA,PRO0883,PRO0903,PRO1341 |
Uniprot Accession | P02768,P02770,Q28522,P49822,P49064,P02769,P35747 |
Uniprot Entry Name | ALBU_HUMAN,ALBU_MACMU,ALBU_RAT,ALBU_FELCA,ALBU_CANLF,ALBU_BOVIN,ALBU_HORSE |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target, Diagnostics Biomarker, INN Index |
Disease | Nephropathy induced by other drugs, medicaments and biological substances, Acute kidney failure, Asphyxia neonatorum, Calculus of kidney, Congenital occlusion of ureteropelvic junction, Crohn's disease, Diabetic Nephropathy, IgA glomerulonephritis, Nephrotic syndrome, Obstructive sleep apnea (adult) (pediatric), Ovarian cancer, Pre-eclampsia, Pregnant state, Type 2 diabetes mellitus, Type 2 diabetes mellitus with diabetic nephropathy |
Gene Ensembl | ENSG00000163631 |
Target Classification | N/A |
The target: ALB, gene name: ALB, also named as HSA, PRO0883, PRO0903, PRO1341. This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.