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Anti-G6PD monoclonal antibody
Pre-made anti-G6PD monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to G6PD/G6PD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T63484-Ab-1/ GM-Tg-hg-T63484-Ab-2 | Anti-Human G6PD monoclonal antibody | Human |
| GM-Tg-rg-T63484-Ab-1/ GM-Tg-rg-T63484-Ab-2 | Anti-Rat G6PD monoclonal antibody | Rat |
| GM-Tg-mg-T63484-Ab-1/ GM-Tg-mg-T63484-Ab-2 | Anti-Mouse G6PD monoclonal antibody | Mouse |
| GM-Tg-cynog-T63484-Ab-1/ GM-Tg-cynog-T63484-Ab-2 | Anti-Cynomolgus/ Rhesus macaque G6PD monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T63484-Ab-1/ GM-Tg-felg-T63484-Ab-2 | Anti-Feline G6PD monoclonal antibody | Feline |
| GM-Tg-cang-T63484-Ab-1/ GM-Tg-cang-T63484-Ab-2 | Anti-Canine G6PD monoclonal antibody | Canine |
| GM-Tg-bovg-T63484-Ab-1/ GM-Tg-bovg-T63484-Ab-2 | Anti-Bovine G6PD monoclonal antibody | Bovine |
| GM-Tg-equg-T63484-Ab-1/ GM-Tg-equg-T63484-Ab-2 | Anti-Equine G6PD monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T63484-Ab-1/ GM-Tg-hg-T63484-Ab-2; GM-Tg-rg-T63484-Ab-1/ GM-Tg-rg-T63484-Ab-2; GM-Tg-mg-T63484-Ab-1/ GM-Tg-mg-T63484-Ab-2; GM-Tg-cynog-T63484-Ab-1/ GM-Tg-cynog-T63484-Ab-2; GM-Tg-felg-T63484-Ab-1/ GM-Tg-felg-T63484-Ab-2; GM-Tg-cang-T63484-Ab-1/ GM-Tg-cang-T63484-Ab-2; GM-Tg-bovg-T63484-Ab-1/ GM-Tg-bovg-T63484-Ab-2; GM-Tg-equg-T63484-Ab-1/ GM-Tg-equg-T63484-Ab-2 |
| Products Name | Anti-G6PD monoclonal antibody |
| Format | mab |
| Target Name | G6PD |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-G6PD monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T63484-Ag-1 | Recombinant multi-species G6PD/ G6PD1 protein |
| ORF Viral Vector | vGMAP000116 | Human G6PD Adenovirus particle |
| ORF Viral Vector | pGMLP000509 | human G6PD Lentivirus plasmid |
| ORF Viral Vector | pGMAP000116 | Human G6PD Adenovirus plasmid |
| ORF Viral Vector | vGMLP000509 | human G6PD Lentivirus particle |
| ORF Viral Vector | pGMLPm005391 | mouse G6pdx Lentivirus plasmid |
| ORF Viral Vector | vGMLPm005391 | mouse G6pdx Lentivirus particle |
Target information
| Target ID | GM-T63484 |
| Target Name | G6PD |
| Gene ID | 2539,14381,24377,701137,119868559,100270776,281179,100059734 |
| Gene Symbol and Synonyms | G28A,G6PD,G6PD1,G6pdx,Gpdx |
| Uniprot Accession | P11413,P05370 |
| Uniprot Entry Name | G6PD_HUMAN,G6PD_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000160211 |
| Target Classification | N/A |
The target: G6PD, gene name: G6PD, also named as G6PD1. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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