Anti-ADCY1/ AC1/ DFNB44 monoclonal antibody

Anti-ADCY1/ AC1/ DFNB44 antibody for FACS & in-vivo assay

Target products collectionGo to ADCY1/ADCY1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T63609-Ab-1/ GM-Tg-hg-T63609-Ab-2Anti-Human ADCY1 monoclonal antibodyHuman
GM-Tg-rg-T63609-Ab-1/ GM-Tg-rg-T63609-Ab-2Anti-Rat ADCY1 monoclonal antibodyRat
GM-Tg-mg-T63609-Ab-1/ GM-Tg-mg-T63609-Ab-2Anti-Mouse ADCY1 monoclonal antibodyMouse
GM-Tg-cynog-T63609-Ab-1/ GM-Tg-cynog-T63609-Ab-2Anti-Cynomolgus/ Rhesus macaque ADCY1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T63609-Ab-1/ GM-Tg-felg-T63609-Ab-2Anti-Feline ADCY1 monoclonal antibodyFeline
GM-Tg-cang-T63609-Ab-1/ GM-Tg-cang-T63609-Ab-2Anti-Canine ADCY1 monoclonal antibodyCanine
GM-Tg-bovg-T63609-Ab-1/ GM-Tg-bovg-T63609-Ab-2Anti-Bovine ADCY1 monoclonal antibodyBovine
GM-Tg-equg-T63609-Ab-1/ GM-Tg-equg-T63609-Ab-2Anti-Equine ADCY1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T63609-Ab-1/ GM-Tg-hg-T63609-Ab-2; GM-Tg-rg-T63609-Ab-1/ GM-Tg-rg-T63609-Ab-2;
GM-Tg-mg-T63609-Ab-1/ GM-Tg-mg-T63609-Ab-2; GM-Tg-cynog-T63609-Ab-1/ GM-Tg-cynog-T63609-Ab-2;
GM-Tg-felg-T63609-Ab-1/ GM-Tg-felg-T63609-Ab-2; GM-Tg-cang-T63609-Ab-1/ GM-Tg-cang-T63609-Ab-2;
GM-Tg-bovg-T63609-Ab-1/ GM-Tg-bovg-T63609-Ab-2; GM-Tg-equg-T63609-Ab-1/ GM-Tg-equg-T63609-Ab-2
Products NameAnti-ADCY1 monoclonal antibody
Target NameADCY1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-ADCY1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ADCY1/ AC1/ DFNB44 VLP (virus-like particle) (Products Developing)

    Target information

    Target IDGM-T63609
    Target NameADCY1
    Gene ID107,432530,305509,697230,101101375,281601,100065563
    Gene Symbol and SynonymsAC1,ADCY1,brl,D11Bwg1392e,DFNB44,I-AC
    Uniprot AccessionQ08828,P19754
    Uniprot Entry NameADCY1_HUMAN,ADCY1_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseNervous system function
    Gene EnsemblENSG00000164742
    Target ClassificationN/A

    The target: ADCY1, gene name: ADCY1, also named as AC1, DFNB44. This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.