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Anti-SSR5/ SSTR5/ SS-5-R monoclonal antibody
Anti-SSR5/ SSTR5/ SS-5-R antibody for FACS & in-vivo assay
Go to SSTR5/SSTR5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T64830-Ab-1/ GM-Tg-hg-T64830-Ab-2 | Anti-Human SSTR5 monoclonal antibody | Human |
| GM-Tg-rg-T64830-Ab-1/ GM-Tg-rg-T64830-Ab-2 | Anti-Rat SSTR5 monoclonal antibody | Rat |
| GM-Tg-mg-T64830-Ab-1/ GM-Tg-mg-T64830-Ab-2 | Anti-Mouse SSTR5 monoclonal antibody | Mouse |
| GM-Tg-cynog-T64830-Ab-1/ GM-Tg-cynog-T64830-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SSTR5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T64830-Ab-1/ GM-Tg-felg-T64830-Ab-2 | Anti-Feline SSTR5 monoclonal antibody | Feline |
| GM-Tg-cang-T64830-Ab-1/ GM-Tg-cang-T64830-Ab-2 | Anti-Canine SSTR5 monoclonal antibody | Canine |
| GM-Tg-bovg-T64830-Ab-1/ GM-Tg-bovg-T64830-Ab-2 | Anti-Bovine SSTR5 monoclonal antibody | Bovine |
| GM-Tg-equg-T64830-Ab-1/ GM-Tg-equg-T64830-Ab-2 | Anti-Equine SSTR5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T64830-Ab-1/ GM-Tg-hg-T64830-Ab-2; GM-Tg-rg-T64830-Ab-1/ GM-Tg-rg-T64830-Ab-2; GM-Tg-mg-T64830-Ab-1/ GM-Tg-mg-T64830-Ab-2; GM-Tg-cynog-T64830-Ab-1/ GM-Tg-cynog-T64830-Ab-2; GM-Tg-felg-T64830-Ab-1/ GM-Tg-felg-T64830-Ab-2; GM-Tg-cang-T64830-Ab-1/ GM-Tg-cang-T64830-Ab-2; GM-Tg-bovg-T64830-Ab-1/ GM-Tg-bovg-T64830-Ab-2; GM-Tg-equg-T64830-Ab-1/ GM-Tg-equg-T64830-Ab-2 |
| Products Name | Anti-SSTR5 monoclonal antibody |
| Format | mab |
| Target Name | SSTR5 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SSTR5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SSR5/ SSTR5/ SS-5-R VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP003594 | human SSTR5 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003594 | human SSTR5 Lentivirus particle |
| ORF Viral Vector | pGMLPm005317 | mouse Sstr5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm005317 | mouse Sstr5 Lentivirus particle |
Target information
| Target ID | GM-T64830 |
| Target Name | SSTR5 |
| Gene ID | 6755,20609,25354,106994905,403454,101090317,510344,100067398 |
| Gene Symbol and Synonyms | Smstr5,Somato,SS-5-R,SS5-R,SS5R,SST5,SSTR5 |
| Uniprot Accession | P35346,P30938,F1MV99 |
| Uniprot Entry Name | SSR5_HUMAN,SSR5_RAT,SSR5_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000162009 |
| Target Classification | GPCR, Tumor-associated antigen (TAA) |
The target: SSTR5, gene name: SSTR5, also named as SS-5-R. Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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